A human pluripotent stem cell-derived skin organoid after 85 days of incubation. The Latest Science.

A human pluripotent stem cell-derived skin organoid after 85 days
of incubation.The epidermis (red) contains outward growing hair follicles
with packets of specialized cells called dermal papilla cells (cyan).

Image contributed by: Karl R. Koehler and Jiyoon Lee,
Department of Otolaryngology and Plastic & Oral Surgery,
Boston Children’s Hospital/Harvard Medical School, USA.
Koehler Laboratory: https://koehler-lab.org

https://www.nature.com/articles/s41586-020-2352-3

The Latest Science provides information on recent advances in any branch of science. The Latest Science is dedicated to the latest cutting edge articles published in journals that has a significant impact on science. 

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Papers of the month:

CRISPR-CasΦ from huge phages is a hypercompact genome editor. Pausch et al. (2020). Science 369: 333-337
https://science.sciencemag.org/content/369/6501/333

Reversing a model of Parkinson’s disease with in situ converted nigral neurons. Qian et al. (2020). Nature 582: 550–556.
https://www.nature.com/articles/s41586-020-2388-4

The stem cell marker Prom1 promotes axon regeneration by down-regulating cholesterol synthesis via Smad signaling. Lee et al. (2020). PNAS 117: 15955-15966.
https://www.pnas.org/content/117/27/15955

Antifungal symbiotic peptide NCR044 exhibits unique structure and multifaceted mechanisms of action that confer plant protection. Velivelli et al. (2020). PNAS: 117: 16043-16054. https://www.pnas.org/content/117/27/16043

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