Neuroscience

Articles:

1374  A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system.
https://www.nature.com/articles/s41587-019-0205-0

1373  A nanoimmunotherapy reduces inflammation in mouse, rabbit, and pig models of atherosclerosis.
https://stm.sciencemag.org/content/11/506/eaaw7736

1372  Adeno-associated viral vector serotype 9–based gene therapy for Niemann-Pick disease type A.
https://stm.sciencemag.org/content/11/506/eaat3738

1371  A study of the functional microbiome in a mouse model of ALS shows that several gut bacteria may modulate the severity of the disease.
https://www.nature.com/articles/s41586-019-1443-5

1370  In vivo evidence for dysregulation of mGluR5 as a biomarker of suicidal ideation.
https://www.pnas.org/content/116/23/11490

1369  Specialized cutaneous Schwann cells initiate pain sensation.
https://science.sciencemag.org/content/365/6454/695

1368  Improved speed, brightness, and photostability of voltage sensors allows simultaneous imaging of many neurons.
https://science.sciencemag.org/content/365/6454/699

1367  The mechanism of β-amyloid–dependent neuronal hyperactivity in mouse models of Alzheimer’s disease is elucidated.
https://science.sciencemag.org/content/365/6453/559

1366  Pharmacological enhancement of KCC2 gene expression exerts therapeutic effects on human Rett syndrome neurons and Mecp2 mutant mice.
https://stm.sciencemag.org/content/11/503/eaau0164

1365  Intestinal infection triggers Parkinson’s disease-like symptoms in Pink1−/− mice.
https://www.nature.com/articles/s41586-019-1405-y

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