Molecular Biology


581  RNA polymerase II has an unexpected function in the nucleolus, helping to drive the expression of ribosomal RNA and to protect nucleolar structure through a mechanism involving triplex R-loop structures.

580  SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation.

579  Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading.

578  Highly Efficient Knockout of a Squid Pigmentation Gene.

577  A large-scale binding and functional map of human RNA-binding proteins.

576  Expanded encyclopaedias of DNA elements in the human and mouse genomes.

575  A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing.

574  CRISPR-CasΦ from huge phages is a hypercompact genome editor.

573  Oncometabolites suppress DNA repair by disrupting local chromatin signalling.

572  Very fast CRISPR on demand enables DNA repair studies at high resolution in space and time at specific genome locations.

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