Molecular Biology


567  A bacteriophage nucleus-like compartment shields DNA from CRISPR nucleases.

566  Harnessing type I CRISPR–Cas systems for genome engineering in human cells.

565  Macrocyclic colibactin induces DNA double-strand breaks via copper-mediated oxidative cleavage.

564  Adenine base editors catalyze cytosine conversions in human cells.

563  A CRISPR-mediated imaging approach, LiveFISH, enables real-time tracking of DNA and RNA in living cells.

562  A unified mechanism for intron and exon definition and back-splicing.

561  Programmed chromosome fission and fusion enable precise large-scale genome rearrangement and assembly.

560  CRISPR-associated nucleases are used to control multiscale properties of DNA-based materials.

559  Drugging an undruggable pocket on KRAS.

558  Rotation tracking of genome-processing enzymes using DNA origami rotors.

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