245 Engineered bacteriophages for treatment of a patient with a disseminated drug-resistant Mycobacterium abscessus.
https://www.nature.com/articles/s41591-019-0437-z
244 Immediate initiation of antiviral therapy in acute HIV infection results in functional and persistent T cell responses.
https://stm.sciencemag.org/content/11/493/eaau0528
243 Ebola vaccination in the Democratic Republic of the Congo.
https://www.pnas.org/content/116/20/10178
242 Filamentous bacteriophages are associated with chronic Pseudomonas lung infections and antibiotic resistance in cystic fibrosis.
https://stm.sciencemag.org/content/11/488/eaau9748
241 HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation.
https://www.nature.com/articles/s41586-019-1027-4
240 An oral macrolide drug targeting the bacterial endosymbiont, Wolbachia, shows efficacy against filarial nematodes in preclinical animal models.
http://stm.sciencemag.org/content/11/483/eaau2086
239 A retrievable device, compatible with nasogastric tube administration, releases grams of drug over weeks while residing in the stomach.
http://stm.sciencemag.org/content/11/483/eaau6267
238 Omadacycline for Community-Acquired Bacterial Pneumonia.
https://www.nejm.org/doi/full/10.1056/NEJMoa1800201
237 Decolonization to Reduce Postdischarge Infection Risk among MRSA Carriers.
https://www.nejm.org/doi/full/10.1056/NEJMoa1716771
236 HIV peptidome-wide association study reveals patient-specific epitope repertoires associated with HIV control.
https://www.pnas.org/content/116/3/944
235 Single-Dose Zoliflodacin (ETX0914) for Treatment of Urogenital Gonorrhea.
https://www.nejm.org/doi/full/10.1056/NEJMoa1706988
234 A Trial of a Triple-Drug Treatment for Lymphatic Filariasis.
https://www.nejm.org/doi/full/10.1056/NEJMoa1706854
233 Epidemiology of the silent polio outbreak in Rahat, Israel, based on modeling of environmental surveillance data.
http://www.pnas.org/content/115/45/E10625
232 Seasonal flu epidemics are more diffuse in larger cities and more intense in smaller cities, where climate has a stronger influence on transmission.
http://science.sciencemag.org/content/362/6410/75
231 The temporal relationship between onchocerciasis and epilepsy: a population-based cohort study.
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(18)30425-0/fulltext
230 Gallium disrupts bacterial iron metabolism and has therapeutic effects in mice and humans with lung infections.
http://stm.sciencemag.org/content/10/460/eaat7520
229 Semisynthetic sensor proteins enable metabolic assays at the point of care.
http://science.sciencemag.org/content/361/6407/1122
228 Optimized arylomycins are a new class of Gram-negative antibiotics.
https://www.nature.com/articles/s41586-018-0483-6
227 Incidence of paediatric pneumococcal meningitis and emergence of new serotypes: a time-series analysis of a 16-year French national survey.
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(18)30349-9/fulltext
226 The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis.
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(18)30348-7/fulltext
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