Cancer Biology

 
1283 In vivo multidimensional CRISPR screens identify Lgals2 as an immunotherapy target in triple-negative breast cancer.
https://www.science.org/doi/10.1126/sciadv.abl8247

1282 Harnessing anti-cytomegalovirus immunity for local immunotherapy against solid tumors.
https://www.pnas.org/doi/10.1073/pnas.2116738119

1281 CKS1 inhibition depletes leukemic stem cells and protects healthy hematopoietic stem cells in acute myeloid leukemia.
https://www.science.org/doi/10.1126/scitranslmed.abn3248

1280 The metastatic spread of breast cancer accelerates during sleep.
https://www.nature.com/articles/s41586-022-04875-y

1279 Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer.
https://www.nejm.org/doi/full/10.1056/NEJMoa2203690?query=featured_home

1278 PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer.
https://www.nejm.org/doi/full/10.1056/NEJMoa2201445?query=featured_home

1277 A nanovaccine for antigen self-presentation and immunosuppression reversal as a personalized cancer immunotherapy strategy.
https://www.nature.com/articles/s41565-022-01098-0

1276 A transistor-like pH-sensitive nanodetergent for selective cancer therapy.
https://www.nature.com/articles/s41565-022-01085-5

1275 Extracellular vesicles from triple negative breast cancer promote pro-inflammatory macrophages associated with better clinical outcome.
https://www.pnas.org/doi/10.1073/pnas.2107394119

1274 Stepwise-edited, human melanoma models reveal mutations’ effect on tumor and microenvironment.
https://www.science.org/doi/10.1126/science.abi8175

1273 Cancer cells use self-inflicted DNA breaks to evade growth limits imposed by genotoxic stress.
https://www.science.org/doi/10.1126/science.abi6378

1272 Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer.
https://www.cell.com/cell/fulltext/S0092-8674(22)00260-4

1271 ESCRT-mediated membrane repair protects tumor-derived cells against T cell attack.
https://www.science.org/doi/10.1126/science.abl3855

1270 Listeria delivers tetanus toxoid protein to pancreatic tumors and induces cancer cell death in mice.
https://www.science.org/doi/10.1126/scitranslmed.abc1600

1269 Diagnosis and prognosis of breast cancer by high-performance serum metabolic fingerprints.
https://www.pnas.org/doi/10.1073/pnas.2122245119

1268 A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells.
https://www.nature.com/articles/s41586-022-04439-0

1267 Intravesical delivery of KDM6A-mRNA via mucoadhesive nanoparticles inhibits the metastasis of bladder cancer.
https://www.pnas.org/content/119/7/e2112696119

1266 Immunomagnetic microscopy of tumor tissues using quantum sensors in diamond.
https://www.pnas.org/content/119/5/e2118876119

1265 Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma.
https://www.cell.com/cell/fulltext/S0092-8674(21)01486-0

1264 Multi-omic machine learning predictor of breast cancer therapy response.
https://www.nature.com/articles/s41586-021-04278-5

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