Cancer Biology

1175 B cell acute lymphoblastic leukemia cells mediate RANK-RANKL–dependent bone destruction.

1174 Interleukin-2 signals converge in a lymphoid–dendritic cell pathway that promotes anticancer immunity.

1173 The bacterial-derived metabolite inosine enhances cancer immunotherapy in mice.

1172 Ageing in humans is associated with an increase in circulating methylmalonic acid, which induces expression of SOX4 and promotes tumour progression.

1171 An effective combination immunotherapy using oncolytic viruses delivers de novo CD19 to promote CD19-CAR T cell therapy against solid tumors in mice.

1170 Lymph protects metastasizing melanoma cells from ferroptosis.

1169 An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma.

1168 Combination of BET inhibitor and vinorelbine improves survival in preclinical models of brain metastases.

1167 Discovery and molecular pharmacology of non-nucleotide STING agonists that induce “closed” STING conformation and antitumor immunity are described.

1166 A cancer evaluation criterion based on T cell receptors is potentially useful for noninvasive early cancer detection.

1165 CytoPAN—Portable cellular analyses for rapid point-of-care cancer diagnosis.

1164 Phosphoprotein-based biomarkers as predictors for cancer therapy.

1163 The safety and clinical effects of administering a multiantigen-targeted T cell therapy to patients with multiple myeloma.

1162 In vivo anticancer activity of a rhodium metalloinsertor in the HCT116 xenograft tumor model.

1161 Tumor cell lysate-loaded immunostimulatory spherical nucleic acids as therapeutics for triple-negative breast cancer.

1160 An engineered version of IL-18 that is resistant to binding by the soluble decoy receptor IL-18BP shows strong anti-tumour activity in mouse models of cancer.

1159 Fasting-mimicking diet and hormone therapy induce breast cancer regression.

1158 An engineered chimeric toxin that cleaves activated mutant and wild-type RAS inhibits tumor growth.

1157 Proteogenomics of Non-smoking Lung Cancer in East Asia Delineates Molecular Signatures of Pathogenesis and Progression.

1156 Integrative Proteomic Characterization of Human Lung Adenocarcinoma.

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