228 The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation.
http://www.cell.com/abstract/S0092-8674(13)00532-1
227 Nontoxic radioactive Listeria is a highly effective therapy against metastatic pancreatic cancer.
http://www.pnas.org/content/110/21/8668
226 MicroRNA profiling of 1,302 human breast tumour samples provides an overview of the miRNA landscape and its regulation, revealing context-dependent interactions, broad prognostic value of miRNA signatures and an important modulatory role for miRNAs in the biology of breast tumours devoid of copy-number aberrations.
http://www.nature.com/nature/journal/v497/n7449/full/nature12108.html
225 The oncolytic and immunotherapeutic vaccinia virus Pexa-Vec (JX-594) induces antibody-mediated complement-dependent cancer cell cytolysis in rabbits and cancer patients, prolonging their survival.
http://stm.sciencemag.org/content/5/185/185ra63.abstract
224 Mutations of histones in some cancers result in inhibition of enzymes that lay down epigenetic marks on chromatin.
http://www.sciencemag.org/content/340/6134/857.abstract
223 Cyclophosphamide Triggers Follicle Activation and “Burnout”; AS101 Prevents Follicle Loss and Preserves Fertility.
http://stm.sciencemag.org/content/5/185/185ra62.abstract
222 In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras–effector interaction.
http://www.pnas.org/content/110/20/8182.abstract
221 Central role of liver in anticancer and radioprotective activities of Toll-like receptor 5 agonist.
http://www.pnas.org/content/110/20/E1857.abstract
220 Aptamer to ErbB-2/HER2 enhances degradation of the target and inhibits tumorigenic growth.
http://www.pnas.org/content/110/20/8170.abstract
219 A Novel Fully Automated Molecular Diagnostic System (AMDS) for Colorectal Cancer Mutation Detection.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0062989
218 Gene network reconstruction reveals cell cycle and antiviral genes as major drivers of cervical cancer.
http://www.nature.com/ncomms/journal/v4/n5/full/ncomms2693.html
217 Neural stem cells home to gliomas in mice where they convert a prodrug to 5-fluorouracil, leading to tumor regression.
http://stm.sciencemag.org/content/5/184/184ra59.abstract
216 Silica-Based Branched Hollow Microfibers as a Biomimetic Extracellular Matrix for Promoting Tumor Cell Growth In Vitro and In Vivo.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201204472/abstract
215 A small molecule that inhibits a mutant enzyme in tumors slows malignant growth by inducing cancer cell differentiation.
http://www.sciencemag.org/content/340/6132/622.abstract
214 Epigenetic changes contribute to a positive feedback loop promoting AP1 activity that contributes to metastasis of squamous cell carcinoma to lymph nodes.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;6/273/ra28
213 Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity.
http://www.nature.com/ng/journal/v45/n5/abs/ng.2591.html
212 Punctuated Evolution of Prostate Cancer Genomes.
http://www.cell.com/abstract/S0092-8674(13)00343-7
211 Specific Capture and Release of Circulating Tumor Cells Using Aptamer-Modified Nanosubstrates.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201300082/abstract
210 Inhibition of tumor growth and metastasis by a self-therapeutic nanoparticle.
http://www.pnas.org/content/110/17/6700.abstract
209 Laponite Nanodisks as an Efficient Platform for Doxorubicin Delivery to Cancer Cells.
http://pubs.acs.org/doi/abs/10.1021/la4001363
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