Cancer Biology

 
942 Enhanced detection of circulating tumor DNA by fragment size analysis.
http://stm.sciencemag.org/content/10/466/eaat4921

941 Nuclear cGAS suppresses DNA repair and promotes tumorigenesis.
https://www.nature.com/articles/s41586-018-0629-6

940 Stromal Modulation Reverses Primary Resistance to Immune Checkpoint Blockade in Pancreatic Cancer.
https://pubs.acs.org/doi/10.1021/acsnano.8b02481

939 Local Blockade of Interleukin 10 and C-X-C Motif Chemokine Ligand 12 with Nano-Delivery Promotes Antitumor Response in Murine Cancers.
https://pubs.acs.org/doi/10.1021/acsnano.8b00967

938 Enhanced Cancer Vaccination by In Situ Nanomicelle-Generating Dissolving Microneedles.
https://pubs.acs.org/doi/10.1021/acsnano.8b04146

937 Enhanced Transdermal Drug Delivery by Transfersome-Embedded Oligopeptide Hydrogel for Topical Chemotherapy of Melanoma.
https://pubs.acs.org/doi/10.1021/acsnano.8b03800

936 Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma.
http://stm.sciencemag.org/content/10/464/eaat3487

935 Chromatin accessibility profiling identifies principles of epigenetic regulation in 23 primary human cancers.
http://science.sciencemag.org/content/362/6413/eaav1898

934 Decreased abundance of TRESK two-pore domain potassium channels in sensory neurons underlies the pain associated with bone metastasis.
http://stke.sciencemag.org/content/11/552/eaao5150

933 Local generation of hydrogen for enhanced photothermal therapy.
https://www.nature.com/articles/s41467-018-06630-2

932 BAP1 links metabolic regulation of ferroptosis to tumour suppression.
https://www.nature.com/articles/s41556-018-0178-0

931 Pan-tumor genomic biomarkers for PD-1 checkpoint blockade–based immunotherapy.
http://science.sciencemag.org/content/362/6411/eaar3593

930 SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer.
https://www.cell.com/immunity/fulltext/S1074-7613(18)30387-X

929 The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells.
https://www.cell.com/immunity/fulltext/S1074-7613(18)30381-9

928 Prostate and lung cancers convert to a drug-resistant, lethal form of cancer through the same reprogramming mechanism.
http://science.sciencemag.org/content/362/6410/91

927 Two Patched molecules engage distinct sites on Hedgehog yielding a signaling-competent complex.
http://science.sciencemag.org/content/362/6410/eaas8843

926 Necroptosis microenvironment directs lineage commitment in liver cancer.
https://www.nature.com/articles/s41586-018-0519-y

925 Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice.
http://science.sciencemag.org/content/361/6409/eaao4227

924 mRNA vaccination with charge-altering releasable transporters elicits human T cell responses and cures established tumors in mice.
http://www.pnas.org/content/115/39/E9153

923 Precancerous neoplastic cells can move through the pancreatic ductal system.
https://www.nature.com/articles/s41586-018-0481-8

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