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Cancer Biology

Cancer Biology

 
1327 Cancer-on-a-chip model shows that the adenomatous polyposis coli mutation impairs T cell engagement and killing of cancer spheroids
https://www.pnas.org/doi/10.1073/pnas.2316500121

1326 An immunogenetic basis for lung cancer risk
https://www.science.org/doi/10.1126/science.adi3808

1325 Siglec-15/sialic acid axis as a central glyco-immune checkpoint in breast cancer bone metastasis
https://www.pnas.org/doi/10.1073/pnas.2312929121

1324 Inhaled mRNA nanoparticles dual-targeting cancer cells and macrophages in the lung for effective transfection
https://www.pnas.org/doi/10.1073/pnas.2304966120

1323 Viral nanoparticle vaccines against S100A9 reduce lung tumor seeding and metastasis
https://www.pnas.org/doi/10.1073/pnas.2221859120

1322 Crosstalk between small-cell lung cancer cells and astrocytes mimics brain development to promote brain metastasis
https://www.nature.com/articles/s41556-023-01241-6

1321 Probiotic-guided CAR-T cells for solid tumor targeting
https://www.science.org/doi/10.1126/science.add7034

1320 A vertebral skeletal stem cell lineage driving metastasis.
https://www.nature.com/articles/s41586-023-06519-1

1319 Epitope engineering of donor haematopoietic stem/progenitor cells endows haematopoietic lineages with selective resistance to CAR T cells or monoclonal antibodies, without affecting protein function or regulation, enabling the targeting of genes that are essential for leukaemia survival and reducing the risk of tumour immune escape.
https://www.nature.com/articles/s41586-023-06496-5

1318 Rationally designed chimeric PI3K-BET bromodomain inhibitors elicit curative responses in MYC-driven lymphoma.
https://www.pnas.org/doi/10.1073/pnas.2306414120

1317 Chromosomal instability in cancer is linked to endoplasmic reticulum stress signalling, immune suppression and metastasis, which is mediated by the cGAS–STING pathway, suppression of which can reduce metastasis.
https://www.nature.com/articles/s41586-023-06464-z

1316 Interferon-ε is a tumour suppressor and restricts ovarian cancer.
https://www.nature.com/articles/s41586-023-06421-w

1315 TREM1 activation of myeloid cells promotes antitumor immunity.
https://www.science.org/doi/10.1126/scitranslmed.add9990

1314 Epitope base editing CD45 in hematopoietic cells enables universal blood cancer immune therapy.
https://www.science.org/doi/10.1126/scitranslmed.adi1145

1313 Lung adenocarcinoma promotion by air pollutants.
https://www.nature.com/articles/s41586-023-05874-3

1312 O-GlcNAcylation promotes tumor immune evasion by inhibiting PD-L1 lysosomal degradation.
https://www.pnas.org/doi/10.1073/pnas.2216796120

1311 Immature natural killer cells promote progression of triple-negative breast cancer.
https://www.science.org/doi/10.1126/scitranslmed.abl4414

1310 Estimates and Projections of the Global Economic Cost of 29 Cancers in 204 Countries and Territories From 2020 to 2050.
https://jamanetwork.com/journals/jamaoncology/fullarticle/2801798

1309 Post-translational modifications reshape the antigenic landscape of the MHC I immunopeptidome in tumors.
https://www.nature.com/articles/s41587-022-01464-2

1308 Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer.
https://www.nature.com/articles/s41586-023-05728-y

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