Cancer Biology

 
1151 Identification of human CD4+ T cell populations with distinct antitumor activity.
https://advances.sciencemag.org/content/6/27/eaba7443

1150 A large feasibility study shows that a cancer blood test and PET-CT imaging can detect some cancers at an early stage.
https://science.sciencemag.org/content/369/6499/eabb9601

1149 Telomere shortening produces an inflammatory environment that increases tumor incidence in zebrafish.
https://www.pnas.org/content/117/26/15066

1148 Reversible suppression of T cell function in the bone marrow microenvironment of acute myeloid leukemia.
https://www.pnas.org/content/117/25/14331

1147 Aptamers against mouse and human tumor-infiltrating myeloid cells as reagents for targeted chemotherapy.
https://stm.sciencemag.org/content/12/548/eaav9760

1146 Molecular and functional extracellular vesicle analysis using nanopatterned microchips monitors tumor progression and metastasis.
https://stm.sciencemag.org/content/12/547/eaaz2878

1145 Metformin selectively inhibits metastatic colorectal cancer with the KRAS mutation by intracellular accumulation through silencing MATE1.
https://www.pnas.org/content/117/23/13012

1144 Ultrasensitive detection of malignant melanoma using PET molecular imaging probes.
https://www.pnas.org/content/117/23/12991

1143 Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa1.
https://www.cell.com/cell-metabolism/fulltext/S1550-4131(20)30189-3

1142 The human tumor microbiome is composed of tumor type–specific intracellular bacteria.
https://science.sciencemag.org/content/368/6494/973

1141 The dopamine receptor antagonist trifluoperazine prevents phenotype conversion and improves survival in mouse models of glioblastoma.
https://www.pnas.org/content/117/20/11085

1140 Natural hybridization reveals incompatible alleles that cause melanoma in swordtail fish.
https://science.sciencemag.org/content/368/6492/731

1139 Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I.
https://www.nature.com/articles/s41586-020-2229-5

1138 Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer.
https://www.cell.com/cell/fulltext/S0092-8674(20)30270-1

1137 Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer.
https://www.cell.com/cell/fulltext/S0092-8674(20)30341-X

1136 The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution.
https://www.cell.com/cell/fulltext/S0092-8674(20)30346-9

1135 Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation.
https://science.sciencemag.org/content/368/6489/387

1134 Germline mutations in the Elongator complex gene ELP1 predispose individuals to the development of childhood medulloblastoma.
https://www.nature.com/articles/s41586-020-2164-5

1133 Integrating genomic features for non-invasive early lung cancer detection.
https://www.nature.com/articles/s41586-020-2140-0

1132 IL-6 blockade reverses bone marrow failure induced by human acute myeloid leukemia.
https://stm.sciencemag.org/content/12/538/eaax5104

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