Ophthalmology

Articles:
102 A Phase 1b/2a Clinical Trial of Dantrolene Sodium in Patients with Wolfram Syndrome.
https://www.medrxiv.org/content/10.1101/2020.10.07.20208694v1

101 Sore eyes as the most significant ocular symptom experienced by people with COVID-19: a comparison between pre-COVID-19 and during COVID-19 states.
https://bmjophth.bmj.com/content/5/1/e000632

100 Electrical stimulation of the visual cortex with a neuroprosthetic device allows artificial vision with shape and motion perception.
https://science.sciencemag.org/content/370/6521/1191

99 Reprogramming to recover youthful epigenetic information and restore vision.
https://www.nature.com/articles/s41586-020-2975-4

98 A gene therapy for inherited blindness using dCas9-VPR–mediated transcriptional activation.
https://advances.sciencemag.org/content/6/34/eaba5614

97 Cell atlas of aqueous humor outflow pathways in eyes of humans and four model species provides insight into glaucoma pathogenesis.
https://www.pnas.org/content/117/19/10339

96 Pharmacologic fibroblast reprogramming into photoreceptors restores vision.
https://www.nature.com/articles/s41586-020-2201-4

95 A device combining soft, wireless wearable electronics with virtual reality offers portable therapeutics for eye disorders.
https://advances.sciencemag.org/content/6/11/eaay1729

94 Galectin-3 initiates epithelial-stromal paracrine signaling to shape the proteolytic microenvironment during corneal repair.
https://stke.sciencemag.org/content/12/590/eaaw7095

93 Retinol binding protein 3 is increased in the retina of patients with diabetes resistant to diabetic retinopathy.
https://stm.sciencemag.org/content/11/499/eaau6627

92 Generation, transcriptome profiling, and functional validation of cone-rich human retinal organoids.
https://www.pnas.org/content/116/22/10824

91 Soluble CX3CL1 gene therapy improves cone survival and function in mouse models of retinitis pigmentosa.
https://www.pnas.org/content/116/20/10140

90 Intein-mediated protein trans-splicing expands adeno-associated virus transfer capacity in the retina.
https://stm.sciencemag.org/content/11/492/eaav4523

89 Mammalian Near-Infrared Image Vision through Injectable and Self-Powered Retinal Nanoantennae.
https://www.cell.com/cell/fulltext/S0092-8674(19)30101-1

88 Single-cell-based analysis provides a comprehensive molecular and cellular taxonomy of the primate retina.
https://www.cell.com/cell/fulltext/S0092-8674(19)30037-6

87 Loss of MPC1 reprograms retinal metabolism to impair visual function.
https://www.pnas.org/content/116/9/3530

86 Ocular fluids from patients with retinal detachment show iron accumulation, and transferrin can be used as a therapeutic adjuvant.
http://advances.sciencemag.org/content/5/1/eaau9940

85 A swarm of slippery micropropellers penetrates the vitreous body of the eye.
http://advances.sciencemag.org/content/4/11/eaat4388

84 Antisense oligonucleotides targeting mutant Ataxin-7 restore visual function in a mouse model of spinocerebellar ataxia type 7.
http://stm.sciencemag.org/content/10/465/eaap8677

83 Thyroid hormone signaling specifies cone subtypes in human retinal organoids.
http://science.sciencemag.org/content/362/6411/eaau6348

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