Ophthalmology

Articles:
92 Generation, transcriptome profiling, and functional validation of cone-rich human retinal organoids.
https://www.pnas.org/content/116/22/10824

91 Soluble CX3CL1 gene therapy improves cone survival and function in mouse models of retinitis pigmentosa.
https://www.pnas.org/content/116/20/10140

90 Intein-mediated protein trans-splicing expands adeno-associated virus transfer capacity in the retina.
https://stm.sciencemag.org/content/11/492/eaav4523

89 Mammalian Near-Infrared Image Vision through Injectable and Self-Powered Retinal Nanoantennae.
https://www.cell.com/cell/fulltext/S0092-8674(19)30101-1

88 Single-cell-based analysis provides a comprehensive molecular and cellular taxonomy of the primate retina.
https://www.cell.com/cell/fulltext/S0092-8674(19)30037-6

87 Loss of MPC1 reprograms retinal metabolism to impair visual function.
https://www.pnas.org/content/116/9/3530

86 Ocular fluids from patients with retinal detachment show iron accumulation, and transferrin can be used as a therapeutic adjuvant.
http://advances.sciencemag.org/content/5/1/eaau9940

85 A swarm of slippery micropropellers penetrates the vitreous body of the eye.
http://advances.sciencemag.org/content/4/11/eaat4388

84 Antisense oligonucleotides targeting mutant Ataxin-7 restore visual function in a mouse model of spinocerebellar ataxia type 7.
http://stm.sciencemag.org/content/10/465/eaap8677

83 Thyroid hormone signaling specifies cone subtypes in human retinal organoids.
http://science.sciencemag.org/content/362/6411/eaau6348

82 Restoration of vision after de novo genesis of rod photoreceptors in mammalian retinas.
https://www.nature.com/articles/s41586-018-0425-3

81 Cholesterol sulfate is a DOCK2 inhibitor that mediates tissue-specific immune evasion in the eye.
http://stke.sciencemag.org/content/11/541/eaao4874

80 Artificial Rod and Cone Photoreceptors with Human‐Like Spectral Sensitivities.
https://onlinelibrary.wiley.com/doi/abs/10.1002/adma.201706764

79 Phase 1 clinical study of an embryonic stem cell–derived retinal pigment epithelium patch in age-related macular degeneration.
https://www.nature.com/articles/nbt.4114

78 BEST1 gene therapy corrects a diffuse retina-wide microdetachment modulated by light exposure.
http://www.pnas.org/content/115/12/E2839

77 Molecular Anatomy of the Developing Human Retina.
http://www.cell.com/developmental-cell/fulltext/S1534-5807(17)30873-0

76 Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy.
https://www.nature.com/articles/nature25013

75 A reversible thermoresponsive sealant for temporary closure of ocular trauma.
http://stm.sciencemag.org/content/9/419/eaan3879

74 Long-term restoration of visual function in end-stage retinal degeneration using subretinal human melanopsin gene therapy.
http://www.pnas.org/content/114/42/11211

73 Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye.
https://elifesciences.org/articles/28899?utm_source=content_alert&utm_medium=email&utm_content=fulltext&utm_campaign=elife-alerts

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