Regenerative Medicine

Articles:

105 A planarian fission protocol shows that the number of progeny and the frequency of fission initiation correlate with parent size, and TGFβ and Wnt signalling components are identified as regulators of fission behaviour.
https://www.nature.com/articles/s41586-019-1478-7

104 Biofabrication of contractile ventricles, heart valves, vascular networks, and organ-scale scaffolds using collagen is explored.
https://science.sciencemag.org/content/365/6452/482

103 Identification of a regeneration-organizing cell in the Xenopus tail.
https://science.sciencemag.org/content/364/6441/653?intcmp=trendmd-sci

102 Regenerative and durable small-diameter graft as an arterial conduit.
https://www.pnas.org/content/116/26/12710

101 Recapitulating bone development through engineered mesenchymal condensations and mechanical cues for tissue regeneration.
https://stm.sciencemag.org/content/11/495/eaav7756

100 Liquid biopsy of circulating exosomes can be used to monitor recovery of ischemic myocardium after transplanting cardiac progenitor cells.
https://stm.sciencemag.org/content/11/493/eaau1168

99 Identification of a regeneration-organizing cell in the Xenopus tail.
https://science.sciencemag.org/content/364/6441/653

98 Single-cell-based imaging and sequencing approaches are used to characterize organoid development and the intestinal regeneration process, which is driven by transient activation of YAP1.
https://www.nature.com/articles/s41586-019-1146-y

97 A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix.
https://stm.sciencemag.org/content/11/489/eaar4953

96 Bioengineered human acellular vessels repopulate with host cells and evolve into self-sustaining living blood vessels in hemodialysis patients.
http://stm.sciencemag.org/content/11/485/eaau6934

95 The genome of the acoel worm Hofstenia miamia elucidates a gene regulatory network that underlies the ability to regenerate.
http://science.sciencemag.org/content/363/6432/eaau6173

94 Phosphate graphene as an intrinsically osteoinductive scaffold for stem cell-driven bone regeneration.
https://www.pnas.org/content/116/11/4855

93 Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair.
https://www.nature.com/articles/s41467-019-09046-8

92 A Unique Collateral Artery Development Program Promotes Neonatal Heart Regeneration.
https://www.cell.com/cell/fulltext/S0092-8674(18)31637-4

91 Stage-dependent cardiac regeneration in Xenopus is regulated by thyroid hormone availability.
https://www.pnas.org/content/116/9/3614

90 ABL kinase inhibition promotes lung regeneration through expansion of an SCGB1A1+ SPC+ cell population following bacterial pneumonia.
https://www.pnas.org/content/116/5/1603

89 Impaired immune surveillance accelerates accumulation of senescent cells and aging.
https://www.nature.com/articles/s41467-018-07825-3#ref-CR67

88 During skin repair, macrophages activate proliferation of a myofibroblast subset that can form adipocytes and promote dermal repair.
http://science.sciencemag.org/content/362/6417/eaar2971

87 Reversion of adult skeletal stem cells to a developmental state underlies the growth of new bone during jaw regeneration, in a process that relies on mechanotransduction via the focal adhesion kinase protein.
https://www.nature.com/articles/s41586-018-0650-9

86 Grxcr1 Promotes Hair Bundle Development by Destabilizing the Physical Interaction between Harmonin and Sans Usher Syndrome Proteins.
https://www.sciencedirect.com/science/article/pii/S2211124718315687

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