Medical Science

Articles:
147 Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis.
http://stm.sciencemag.org/content/9/420/eaal3765

146 Hemophilia B Gene Therapy with a High-Specific-Activity Factor IX Variant.
http://www.nejm.org/doi/full/10.1056/NEJMoa1708538

145 Tezacaftor–Ivacaftor in Residual-Function Heterozygotes with Cystic Fibrosis.
http://www.nejm.org/doi/full/10.1056/NEJMoa1709847

144 Tezacaftor–Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del.
http://www.nejm.org/doi/full/10.1056/NEJMoa1709846

143 Tofacitinib for Psoriatic Arthritis in Patients with an Inadequate Response to TNF Inhibitors.
http://www.nejm.org/doi/full/10.1056/NEJMoa1615977?query=featured_home

142 Engineering a highly elastic human protein–based sealant for surgical applications.
http://stm.sciencemag.org/content/9/410/eaai7466

141 Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia.
http://www.nejm.org/doi/full/10.1056/NEJMoa1704559

140 Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9 (for organ transplant in humans).
http://science.sciencemag.org/content/early/2017/08/09/science.aan4187

139 Trial of Tocilizumab in Giant-Cell Arteritis.
http://www.nejm.org/doi/full/10.1056/NEJMoa1613849

138 High serum serotonin in sudden infant death syndrome.
http://www.pnas.org/content/114/29/7695.abstract

137 Lithium Use in Pregnancy and the Risk of Cardiac Malformations.
http://www.nejm.org/doi/full/10.1056/NEJMoa1612222

136 Oral Glucocorticoid–Sparing Effect of Benralizumab in Severe Asthma.
http://www.nejm.org/doi/full/10.1056/NEJMoa1703501

135 Restoring auditory cortex plasticity in adult mice by restricting thalamic adenosine signaling.
http://science.sciencemag.org/content/356/6345/1352

134 Oil-Based or Water-Based Contrast for Hysterosalpingography in Infertile Women.
http://www.nejm.org/doi/full/10.1056/NEJMoa1612337

133 Smoking prevalence and attributable disease burden in 195 countries and territories, 1990–2015: a systematic analysis from the Global Burden of Disease Study 2015.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)30260-X/fulltext

132 Glycosaminoglycan-based hydrogels capture inflammatory chemokines and rescue defective wound healing in mice.
http://stm.sciencemag.org/content/9/386/eaai9044

131 Quarter-dose quadruple combination therapy for initial treatment of hypertension.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)30260-X/fulltext

130 Gene Therapy in a Patient with Sickle Cell Disease.
http://www.nejm.org/doi/full/10.1056/NEJMoa1609677

129 Baricitinib versus Placebo or Adalimumab in Rheumatoid Arthritis.
http://www.nejm.org/doi/full/10.1056/NEJMoa1608345

128 Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis.
http://www.nejm.org/doi/full/10.1056/NEJMoa1601277

127 Hand-powered ultralow-cost paper centrifuge.
http://www.nature.com/articles/s41551-016-0009

126 SDF-1/CXCR4 axis induces human dental pulp stem cell migration through FAK/PI3K/Akt and GSK3β/β-catenin pathways.
http://www.nature.com/articles/srep40161

125 Interleukin-33-induced expression of PIBF1 by decidual B cells protects against preterm labor.
http://www.nature.com/nm/journal/v23/n1/abs/nm.4244.html

124 A bioengineered living cell construct activates an acute wound healing response in venous leg ulcers.
http://stm.sciencemag.org/content/9/371/eaaf8611

123 Five-coordinate H64Q neuroglobin as a ligand-trap antidote for carbon monoxide poisoning.
http://stm.sciencemag.org/content/8/368/368ra173

122 Reloadable multidrug capturing delivery system for targeted ischemic disease treatment.
http://stm.sciencemag.org/content/8/365/365ra160

121 An injectable shear-thinning biomaterial for endovascular embolization.
http://stm.sciencemag.org/content/8/365/365ra156

120 Interventions to prevent and reduce physician burnout: a systematic review and meta-analysis.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)31279-X/fulltext

119 Calciprotein particles as potential etiologic agents of idiopathic preterm birth.
http://stm.sciencemag.org/content/8/364/364ra154

118 Purinergic receptors in the carotid body as a new drug target for controlling hypertension.
http://www.nature.com/nm/journal/v22/n10/abs/nm.4173.html

117 Prevalence of Pulmonary Embolism among Patients Hospitalized for Syncope.
http://www.nejm.org/doi/full/10.1056/NEJMoa1602172?query=featured_home

116 Chronic Cough.
http://www.nejm.org/doi/full/10.1056/NEJMcp1414215?query=featured_home

115 Birefringence microscopy platform for assessing airway smooth muscle structure and function in vivo.
http://stm.sciencemag.org/content/8/359/359ra131

114 Fresh versus Frozen Embryos for Infertility in the Polycystic Ovary Syndrome.
http://www.nejm.org/doi/full/10.1056/NEJMoa1513873

113 The economic burden of physical inactivity.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)30383-X/fulltext

112 Does physical activity attenuate, or even eliminate, the detrimental association of sitting time with mortality?
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)30370-1/fulltext

111 Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)30175-1/fulltext

110 Phase 3 Trials of Ixekizumab in Moderate-to-Severe Plaque Psoriasis.
http://www.nejm.org/doi/full/10.1056/NEJMoa1512711

109 Indacaterol–Glycopyrronium versus Salmeterol–Fluticasone for COPD.
http://www.nejm.org/doi/full/10.1056/NEJMoa1516385

108 Early rheumatoid arthritis treated with tocilizumab, methotrexate, or their combination.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)30363-4/abstract

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