Medical Science

Articles:
131 Quarter-dose quadruple combination therapy for initial treatment of hypertension.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)30260-X/fulltext

130 Gene Therapy in a Patient with Sickle Cell Disease.
http://www.nejm.org/doi/full/10.1056/NEJMoa1609677

129 Baricitinib versus Placebo or Adalimumab in Rheumatoid Arthritis.
http://www.nejm.org/doi/full/10.1056/NEJMoa1608345

128 Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis.
http://www.nejm.org/doi/full/10.1056/NEJMoa1601277

127 Hand-powered ultralow-cost paper centrifuge.
http://www.nature.com/articles/s41551-016-0009

126 SDF-1/CXCR4 axis induces human dental pulp stem cell migration through FAK/PI3K/Akt and GSK3β/β-catenin pathways.
http://www.nature.com/articles/srep40161

125 Interleukin-33-induced expression of PIBF1 by decidual B cells protects against preterm labor.
http://www.nature.com/nm/journal/v23/n1/abs/nm.4244.html

124 A bioengineered living cell construct activates an acute wound healing response in venous leg ulcers.
http://stm.sciencemag.org/content/9/371/eaaf8611

123 Five-coordinate H64Q neuroglobin as a ligand-trap antidote for carbon monoxide poisoning.
http://stm.sciencemag.org/content/8/368/368ra173

122 Reloadable multidrug capturing delivery system for targeted ischemic disease treatment.
http://stm.sciencemag.org/content/8/365/365ra160

121 An injectable shear-thinning biomaterial for endovascular embolization.
http://stm.sciencemag.org/content/8/365/365ra156

120 Interventions to prevent and reduce physician burnout: a systematic review and meta-analysis.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)31279-X/fulltext

119 Calciprotein particles as potential etiologic agents of idiopathic preterm birth.
http://stm.sciencemag.org/content/8/364/364ra154

118 Purinergic receptors in the carotid body as a new drug target for controlling hypertension.
http://www.nature.com/nm/journal/v22/n10/abs/nm.4173.html

117 Prevalence of Pulmonary Embolism among Patients Hospitalized for Syncope.
http://www.nejm.org/doi/full/10.1056/NEJMoa1602172?query=featured_home

116 Chronic Cough.
http://www.nejm.org/doi/full/10.1056/NEJMcp1414215?query=featured_home

115 Birefringence microscopy platform for assessing airway smooth muscle structure and function in vivo.
http://stm.sciencemag.org/content/8/359/359ra131

114 Fresh versus Frozen Embryos for Infertility in the Polycystic Ovary Syndrome.
http://www.nejm.org/doi/full/10.1056/NEJMoa1513873

113 The economic burden of physical inactivity.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)30383-X/fulltext

112 Does physical activity attenuate, or even eliminate, the detrimental association of sitting time with mortality?
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)30370-1/fulltext

111 Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)30175-1/fulltext

110 Phase 3 Trials of Ixekizumab in Moderate-to-Severe Plaque Psoriasis.
http://www.nejm.org/doi/full/10.1056/NEJMoa1512711

109 Indacaterol–Glycopyrronium versus Salmeterol–Fluticasone for COPD.
http://www.nejm.org/doi/full/10.1056/NEJMoa1516385

108 Early rheumatoid arthritis treated with tocilizumab, methotrexate, or their combination.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)30363-4/abstract

107 Blue light reduces organ injury from ischemia and reperfusion.
http://www.pnas.org/content/113/19/5239.abstract

106 Tocilizumab for induction and maintenance of remission in giant cell arteritis.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)00560-2/abstract

105 Sustained-release dexamfetamine in the treatment of chronic cocaine-dependent patients on heroin-assisted treatment.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)00205-1/abstract

104 In-vivo oesophageal regeneration in a human being by use of a non-biological scaffold and extracellular matrix.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(15)01036-3/abstract

103 Routine pre-procedural rectal indometacin versus selective post-procedural rectal indometacin to prevent pancreatitis in patients undergoing endoscopic retrograde cholangiopancreatography: a multicentre, single-blinded, randomised controlled trial.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)30310-5/abstract

102 A Randomized Trial Comparing Skin Antiseptic Agents at Cesarean Delivery.
http://www.nejm.org/doi/full/10.1056/NEJMoa1511048

101 Effects of Testosterone Treatment in Older Men.
http://www.nejm.org/doi/full/10.1056/NEJMoa1506119

100 NETosis and lack of DNase activity are key factors in Echis carinatus venom-induced tissue destruction.
http://www.nature.com/ncomms/2016/160419/ncomms11361/full/ncomms11361.html

99 Individualizing liver transplant immunosuppression using a phenotypic personalized medicine platform.
http://stm.sciencemag.org/content/8/333/333ra49

98 Mitochondrial iron chelation ameliorates cigarette smoke–induced bronchitis and emphysema in mice.
http://www.nature.com/nm/journal/v22/n2/full/nm.4021.html

97 Induction of labour at term with oral misoprostol versus a Foley catheter.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)00084-2/abstract

96 A Randomized Trial of Low-Cost Mesh in Groin Hernia Repair.
http://www.nejm.org/doi/full/10.1056/NEJMoa1505126

95 Metformin versus Placebo in Obese Pregnant Women without Diabetes Mellitus.
http://www.nejm.org/doi/full/10.1056/NEJMoa1509819

94 Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity.
http://www.nejm.org/doi/full/10.1056/NEJMoa1510991

93 Secukinumab, an Interleukin-17A Inhibitor, in Ankylosing Spondylitis.
http://www.nejm.org/doi/full/10.1056/NEJMoa1505066

92 A Trial of Wound Irrigation in the Initial Management of Open Fracture Wounds.
http://www.nejm.org/doi/full/10.1056/NEJMoa1508502

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