255 The immunometabolite itaconate inhibits a key enzyme in Mycobacterium tuberculosis lipid metabolism.
https://science.sciencemag.org/content/366/6465/589
254 The gut microbiome regulates host glucose homeostasis via peripheral serotonin.
https://www.pnas.org/content/116/40/19802
253 The hormone GDF15 promotes tolerance and survival during conditions of infection and sepsis by modulating systemic levels of plasma triglycerides.
https://www.cell.com/cell/fulltext/S0092-8674(19)30832-3
252 Dietary methionine influences therapy in mouse cancer models and alters human metabolism.
https://www.nature.com/articles/s41586-019-1437-3
251 BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals.
https://www.pnas.org/content/116/31/15469
250 Lowering of ceramide improves diabetes.
https://science.sciencemag.org/content/365/6451/386?intcmp=trendmd-sci
249 Genetic, pharmacological and metabolomics experiments reveal that the malate–aspartate shuttle and mitochondrial citrate export support the differentiation of mouse T helper 1 cells, whereas succinate dehydrogenase enforces their terminal effector function.
https://www.nature.com/articles/s41586-019-1311-3
248 De novo design of symmetric ferredoxins that shuttle electrons in vivo.
https://www.pnas.org/content/116/29/14557
247 PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension.
https://www.pnas.org/content/116/27/13394
246 Microbial production of methyl anthranilate, a grape flavor compound.
https://www.pnas.org/content/116/22/10749
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