243 Elevated activity of the methionine cycle is essential for cancer stem cell tumorigenesis and represents a therapeutic vulnerability.
https://www.nature.com/articles/s41591-019-0423-5
242 Constrained sialic acid donors enable selective synthesis of α-glycosides.
https://science.sciencemag.org/content/364/6441/677
241 Conformationally supple glucose monomers enable synthesis of the smallest cyclodextrins.
https://science.sciencemag.org/content/364/6441/674
240 The short-chain fatty acid propionate increases glucagon and FABP4 production, impairing insulin action in mice and humans.
https://stm.sciencemag.org/content/11/489/eaav0120
239 Glutaminase Deficiency Caused by Short Tandem Repeat Expansion in GLS.
https://www.nejm.org/doi/full/10.1056/NEJMoa1806627
238 Antibiotic treatment affects the expression levels of copper transporters and the isotopic composition of copper in the colon of mice.
https://www.pnas.org/content/116/13/5955
237 Discovery of a pathway for terminal-alkyne amino acid biosynthesis.
https://www.nature.com/articles/s41586-019-1020-y
236 Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O2 activation.
https://www.pnas.org/content/116/12/5370
235 The integration of liver and plasma quantitative lipidomic and proteomic data from 107 distinct mouse strains provides important insights into regulators of mammalian lipid metabolism.
https://www.nature.com/articles/s41586-019-0984-y
234 LINC00116 codes for a mitochondrial peptide linking respiration and lipid metabolism.
https://www.pnas.org/content/116/11/4940
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