Structural Biology

Articles:
146 Insight into the Structure of the “Unstructured” Tau Protein.
https://www.cell.com/structure/fulltext/S0969-2126(19)30309-0?utm_medium=homepage

145 Structure and mechanism of the cation–chloride cotransporter NKCC1.
https://www.nature.com/articles/s41586-019-1438-2

144 Drugging an undruggable pocket on KRAS.
https://www.pnas.org/content/116/32/15823

143 Proton activated channel with roles in ischemic injury is identified.
https://science.sciencemag.org/content/364/6438/395

142 Structure of the IFNγ receptor complex guides design of biased agonists.
https://www.nature.com/articles/s41586-019-0988-7

141 A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels.
http://science.sciencemag.org/content/363/6429/875

140 Tc toxin activation requires unfolding and refolding of a β-propeller.
https://www.nature.com/articles/s41586-018-0556-6

139 Cryo-EM structure of the Ebola virus nucleoprotein–RNA complex at 3.6 Å resolution.
https://www.nature.com/articles/s41586-018-0630-0

138 Cryo-EM structure of the Ebola virus nucleoprotein–RNA complex at 3.6 Å resolution.
https://www.nature.com/articles/s41586-018-0630-0

137 Structures provide insight into how voltage-gated sodium channels function and how they can be inhibited.
http://science.sciencemag.org/content/362/6412/eaau2596

136 Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1.
http://science.sciencemag.org/content/362/6412/eaau2486

135 A cryo-electron microscopy structure of the insect Orco subunit, which forms ion channels with diverse olfactory receptors, reveals a tetrameric cation channel and sheds light on insect olfaction.
https://www.nature.com/articles/s41586-018-0420-8

134 Structure of the origin recognition complex bound to DNA replication origin.
https://www.nature.com/articles/s41586-018-0293-x

133 Structure of a human synaptic GABAA receptor.
https://www.nature.com/articles/s41586-018-0255-3

132 Cryo-EM structure of a herpesvirus capsid at 3.1 Å.
http://science.sciencemag.org/content/360/6384/eaao7283

131 The structure of huntingtin in complex with an interactor is determined to an overall resolution of 4 Å, paving the way for improved understanding of the cellular functions of this protein.
https://www.nature.com/articles/nature25502

130 Structures of human PRC2 with its cofactors AEBP2 and JARID2.
http://science.sciencemag.org/content/359/6378/940

129 Structure of the cold- and menthol-sensing ion channel TRPM8.
http://science.sciencemag.org/content/359/6372/237

128 High-resolution D4 dopamine receptor crystal structures facilitate the discovery of new ligands.
http://science.sciencemag.org/content/358/6361/381

127 The crystal structure of the bacterial potassium import complex KdpFABC shows how ATP hydrolysis is coupled to potassium transport to maintain cellular homeostasis under low potassium conditions.
http://www.nature.com/nature/journal/v546/n7660/full/nature22970.html

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