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Structural Biology

Structural Biology

Articles:
167 De novo design of luciferases using deep learning.
https://www.nature.com/articles/s41586-023-05696-3

166 Structure-based design of bitopic ligands for the µ-opioid receptor.
https://www.nature.com/articles/s41586-022-05588-y

165 Structures of the entire human opioid receptor family.
https://www.cell.com/cell/fulltext/S0092-8674(22)01545-8

164 Mapping the Accessory Proteins (Orfs) of Severe Acute Respiratory Syndrome Coronavirus 2.
https://www.liebertpub.com/doi/10.1089/regen.2022.0056

163 Geometric deep learning of RNA structure.
http://science.sciencemag.org/content/373/6558/1047

162 Computational design of a synthetic PD-1 agonist.
https://www.pnas.org/content/118/29/e2102164118

161 Structural basis of omega-3 fatty acid transport across the blood–brain barrier.
https://www.nature.com/articles/s41586-021-03650-9

160 A structure of RNA polymerase II in complex with spliceosomal particle U1 snRNP reveals how transcription and RNA splicing are coupled.
https://science.sciencemag.org/content/371/6526/305

159 Structures of the iron transporter ferroportin and the peptide hormone hepcidin suggest how iron homeostasis is tightly regulated.
https://www.nature.com/articles/s41586-020-2668-z

158 Computational design of transmembrane pores.
https://www.nature.com/articles/s41586-020-2646-5

157 Structures of human pannexin 1 reveal ion pathways and mechanism of gating.
https://www.nature.com/articles/s41586-020-2357-y

156 A mass spectrometry analysis reveals the glycan composition at all glycosylation sites on the SARS-CoV-2 spike protein.
https://science.sciencemag.org/content/369/6501/330

155 Structure of the RNA-dependent RNA polymerase from COVID-19 virus.
https://science.sciencemag.org/content/368/6492/779

154 The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage.
https://www.pnas.org/content/117/19/10254

153 The Structure of the Membrane Protein of SARS-CoV-2 Resembles the Sugar Transporter semiSWEET.
https://www.preprints.org/manuscript/202004.0512/v1

152 Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors.
https://science.sciencemag.org/content/368/6489/409

151 Structure of mouse coronavirus spike protein complexed with receptor reveals mechanism for viral entry.
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1008392

150 Structural insight into arenavirus replication machinery.
https://www.nature.com/articles/s41586-020-2114-2

149 Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-Gi Complex Structures.
https://www.cell.com/cell/fulltext/S0092-8674(20)30055-6

148 Cryo-EM Structure of the Human Cannabinoid Receptor CB2-Gi Signaling Complex.
https://www.cell.com/cell/fulltext/S0092-8674(20)30054-4

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