Biotechnology

Articles:

448  Engineering the stereoisomeric structure of seed oil to mimic human milk fat.
https://www.pnas.org/content/116/42/20947

447  Data storage in DNA with fewer synthesis cycles using composite DNA letters.
https://www.nature.com/articles/s41587-019-0240-x

446  Polymer nanocapsules, assembled around a ribonucleoprotein complex of Cas9 nuclease and a single-guide RNA, enable safe and efficient gene editing in vitro and in vivo.
https://www.nature.com/articles/s41565-019-0539-2

445  Engineering energetically efficient transport of dicarboxylic acids in yeast Saccharomyces cerevisiae.
https://www.pnas.org/content/116/39/19415

444  Programmable RNA editing by recruiting endogenous ADAR using engineered RNAs.
https://www.nature.com/articles/s41587-019-0178-z

443  Engineered zinc finger nucleases achieve 98% knockout of a target gene in human T cells without detectable off-target activity.
https://www.nature.com/articles/s41587-019-0186-z

442  A divalent siRNA architecture enables sustained silencing of gene expression in deep regions of the brain.
https://www.nature.com/articles/s41587-019-0205-0

441  Encapsulation of Plasmid DNA by Nanoscale Metal–Organic Frameworks for Efficient Gene Transportation and Expression.
https://onlinelibrary.wiley.com/doi/10.1002/adma.201901570

440  RNA-guided DNA insertion with CRISPR-associated transposases.
https://science.sciencemag.org/content/365/6448/48

439  Programmable bacteria induce durable tumor regression and systemic antitumor immunity.
https://www.nature.com/articles/s41591-019-0498-z

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