417 The degree to which a genome can tolerate mutations is inversely correlated with the fitness of a yeast strain.
https://science.sciencemag.org/content/366/6464/490
416 Search-and-replace genome editing without double-strand breaks or donor DNA.
https://www.nature.com/articles/s41586-019-1711-4
415 The piRNA Response to Retroviral Invasion of the Koala Genome.
https://www.cell.com/cell/fulltext/S0092-8674(19)31008-6
414 An Ancient Genome from the Indus Valley Civilization.
https://www.cell.com/cell/fulltext/S0092-8674(19)31078-5
413 Polymer nanocapsules, assembled around a ribonucleoprotein complex of Cas9 nuclease and a single-guide RNA, enable safe and efficient gene editing in vitro and in vivo.
https://www.nature.com/articles/s41565-019-0539-2
412 Acoustic reporter genes enable noninvasive ultrasound imaging of gene expression in mammalian cells.
https://science.sciencemag.org/content/365/6460/1469
411 Maleness-on-the-Y (MoY) orchestrates male sex determination in major agricultural fruit fly pests.
https://science.sciencemag.org/content/365/6460/1457
410 Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility.
https://science.sciencemag.org/content/365/6460/eaav7188
409 A genome-wide association study of same-sex sexual behavior identifies loci associated with human sexual orientation.
https://science.sciencemag.org/content/365/6456/eaat7693
408 Programmed chromosome fission and fusion enable precise large-scale genome rearrangement and assembly.
https://science.sciencemag.org/content/365/6456/922
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