74 Efficacy of vaccination with recombinant vaccinia and fowlpox vectors expressing NY-ESO-1 antigen in ovarian cancer and melanoma patients.
http://www.pnas.org/content/109/15/5797.abstract
73 A targeted nanoparticle containing docetaxel displays antitumor activity in animals and differentiated pharmacological properties in patients with advanced solid tumors.
http://stm.sciencemag.org/content/4/128/128ra39.abstract
72 High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
http://www.pnas.org/content/109/14/5423.abstract
71 Chronic Activation of mTOR Complex 1 Is Sufficient to Cause Hepatocellular Carcinoma in Mice.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;5/217/ra24
70 A novel compound, Imipramine Blue, enhances efficacy of chemotherapy in a single treatment against a rodent astrocytoma model in vivo by inhibiting cell invasion.
http://stm.sciencemag.org/content/4/127/127ra36.abstract
69 The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
http://www.nature.com/nature/journal/v483/n7391/full/nature11003.html
68 Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes
http://www.nature.com/nature/journal/v483/n7391/full/nature10910.html
67 Systematic identification of genomic markers of drug sensitivity in cancer cells.
http://www.nature.com/nature/journal/v483/n7391/full/nature11005.html
66 Plasmonic Nanopowders for Photothermal Therapy of Tumors.
http://pubs.acs.org/doi/abs/10.1021/la300022k
65 Transferred melanoma-specific CD8+ T cells persist, mediate tumor regression, and acquire central memory phenotype.
http://www.pnas.org/content/109/12/4592.abstract
64 Activation of GATA binding protein 6 (GATA6) sustains oncogenic lineage-survival in esophageal adenocarcinoma.
http://www.pnas.org/content/109/11/4251.abstract
63 Findings reveal that the turmeric spice component curcumin can act in a combinatorial manner to disrupt histone modification and androgen receptor signaling to control prostate cancer growth.
http://cancerres.aacrjournals.org/content/72/5/1248.abstract
62 p53 Inhibits Angiogenesis by Inducing the Production of Arresten.
http://cancerres.aacrjournals.org/content/72/5/1270.abstract
61 Cathepsin B Inhibition Limits Bone Metastasis in Breast Cancer.
http://cancerres.aacrjournals.org/content/72/5/1199.abstract
60 Ovarian cancer progression is controlled by phenotypic changes in dendritic cells.
http://jem.rupress.org/content/209/3/495.abstract
59 Accurate Detection of Carcinoma Cells by Use of a Cell Microarray Chip.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0032370
58 In silico Experimentation of Glioma Microenvironment Development and Anti-tumor Therapy.
http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1002355
57 The cell cycle inhibitor p57 is induced by Akt but suppressed by ERK to control growth factor–induced proliferation and limit oncogenic behavior.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;5/214/ra19
56 Short-term starvation increases the effectiveness of chemotherapy against a wide range of tumor cell types.
http://stm.sciencemag.org/content/4/124/124ra27.abstract
55 Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma.
http://www.nejm.org/doi/full/10.1056/NEJMoa1112824
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