94 Methylation tags at long-distance gene regulatory elements provide a signature specific to cancer cells.
http://www.sciencemag.org/content/336/6082/736.abstract
93 Gene therapy using P140K-modified hematopoietic progenitor cells is chemoprotective, enabling glioblastoma patients to withstand myelotoxic doses of chemotherapy.
http://stm.sciencemag.org/content/4/133/133ra57.abstract
92 A targeted therapy for a virus-induced cancer involves blockade of the cellular oncoprotein survivin.
http://stm.sciencemag.org/content/4/133/133ra56.abstract
91 A targeted therapy for a virus-induced cancer involves blockade of the cellular oncoprotein survivin.
http://stm.sciencemag.org/content/4/133/133ra56.abstract
90 Using virally expressed melanoma cDNA libraries to identify tumor-associated antigens that cure melanoma.
http://www.nature.com/nbt/journal/v30/n4/abs/nbt.2157.html
89 The translational landscape of mTOR signalling steers cancer initiation and metastasis.
http://www.nature.com/nature/journal/v485/n7396/full/nature10912.html
88 Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells.
http://www.nature.com/srep/2012/120412/srep00362/full/srep00362.html
87 Reliable detection of subclonal single-nucleotide variants in tumour cell populations.
http://www.nature.com/ncomms/journal/v3/n5/full/ncomms1814.html
86 Delivery of Multiple siRNAs Using Lipid-Coated PLGA Nanoparticles for Treatment of Prostate Cancer.
http://pubs.acs.org/doi/abs/10.1021/nl2035354
85 A Novel Clinically Translatable Fluorescent Nanoparticle for Targeted Molecular Imaging of Tumors in Living Subjects.
http://pubs.acs.org/doi/abs/10.1021/nl203526f
84 Mesoporous Multifunctional Upconversion Luminescent and Magnetic “Nanorattle” Materials for Targeted Chemotherapy.
http://pubs.acs.org/doi/abs/10.1021/nl202949y
83 Full Surface Embedding of Gold Clusters on Silicon Nanowires for Efficient Capture and Photothermal Therapy of Circulating Tumor Cells.
http://pubs.acs.org/doi/abs/10.1021/nl2045759
82 Gold Nanoparticles-Decorated Silicon Nanowires as Highly Efficient Near-Infrared Hyperthermia Agents for Cancer Cells Destruction.
http://pubs.acs.org/doi/abs/10.1021/nl204203t
81 Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma.
http://www.pnas.org/content/109/17/6656.abstract
80 The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors.
http://www.pnas.org/content/109/17/6662.abstract
79 Pre-Diagnostic Plasma 25-Hydroxyvitamin D Levels and Risk of Non-Melanoma Skin Cancer in Women.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0035211
78 TumorHoPe: A Database of Tumor Homing Peptides.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0035187
77 Use of Cell-SELEX to Generate DNA Aptamers as Molecular Probes of HPV-Associated Cervical Cancer Cells.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0036103
76 Quantum-dot-tagged reduced graphene oxide (QD-rGO) nanocomposites internalized into targeted tumor cells display bright fluorescence from the QDs; by absorbing NIR radiation incident on the rGO and converting it into heat, they also cause simultaneous cell death and fluorescence reduction. The nanocomposite is thus capable of tumor imaging, photothermal therapy and in situ monitoring of treatment in progress.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201104070/abstract
75 Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells.
http://www.nature.com/srep/2012/120412/srep00362/full/srep00362.html
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