Cancer Biology

 
965 Deep learning using tumor HLA peptide mass spectrometry datasets improves neoantigen identification
https://www.nature.com/articles/nbt.4313

964 An oncolytic herpesvirus expressing E-cadherin improves survival in mouse models of glioblastoma.
https://www.nature.com/articles/nbt.4302

963 Central body fatness is a stronger predictor of cancer risk than overall body size.
https://www.nature.com/articles/s41467-018-08159-w

962 Blocking IL-1β reverses the immunosuppression in mouse breast cancer and synergizes with anti–PD-1 for tumor abrogation.
https://www.pnas.org/content/116/4/1361

961 Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody.
https://www.pnas.org/content/116/4/1370

960 IL-15 is a component of the inflammatory milieu in the tumor microenvironment promoting antitumor responses.
https://www.pnas.org/content/116/2/599

959 Tissue-resident memory CD8+ T cells promote melanoma–immune equilibrium in skin.
https://www.nature.com/articles/s41586-018-0812-9

958 A large network of bacterial proteins promotes endogenous DNA damage and mutations when upregulated, acting like protein carcinogens, and has human homologs that form a cancer predictive network.
https://www.cell.com/cell/fulltext/S0092-8674(18)31622-2

957 Actively personalized vaccination trial for newly diagnosed glioblastoma.
https://www.nature.com/articles/s41586-018-0810-y

956 Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial.
https://www.nature.com/articles/s41586-018-0792-9

955 De novo design of potent and selective mimics of IL-2 and IL-15.
https://www.nature.com/articles/s41586-018-0830-7

954 Deletion of the A-to-I double-stranded RNA-editing enzyme ADAR1 sensitizes tumour cells to immunotherapy.
https://www.nature.com/articles/s41586-018-0768-9

953 Organoid Modeling of the Tumor Immune Microenvironment.
https://www.cell.com/cell/fulltext/S0092-8674(18)31513-7

952 Cancer-associated fibroblasts suppress SOX2-induced dysplasia in a lung squamous cancer coculture.
https://www.pnas.org/content/115/50/E11671

951 Altered ubiquitination of RAS GTPases is implicated in cancer drug resistance.
http://science.sciencemag.org/content/362/6419/1171

950 Human tumor genomics and zebrafish modeling identify SPRED1 loss as a driver of mucosal melanoma.
http://science.sciencemag.org/content/362/6418/1055

949 Single-cell multiomics sequencing and analyses of human colorectal cancer.
http://science.sciencemag.org/content/362/6418/1060

948 Mannose impairs tumour growth and enhances chemotherapy.
https://www.nature.com/articles/s41586-018-0729-3

947 Cancer-associated mutations are surprisingly common in normal esophageal epithelium from human donors.
http://science.sciencemag.org/content/362/6417/911

946 Human-like hyperplastic prostate with low ZIP1 induced solely by Zn deficiency in rats.
http://www.pnas.org/content/115/47/E11091

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