38 Letrozole versus Clomiphene for Infertility in the Polycystic Ovary Syndrome.
http://www.nejm.org/doi/full/10.1056/NEJMoa1313517
37 Pasireotide for Postoperative Pancreatic Fistula.
http://www.nejm.org/doi/full/10.1056/NEJMoa1313688
36 Characterizing asthma from a drop of blood using neutrophil chemotaxis.
http://www.pnas.org/content/111/16/5813.abstract
35 Close-Field Electroporation Gene Delivery Using the Cochlear Implant Electrode Array Enhances the Bionic Ear.
http://stm.sciencemag.org/content/6/233/233ra54
34 Experimental orthotopic transplantation of a tissue-engineered oesophagus in rats.
http://www.nature.com/ncomms/2014/140415/ncomms4562/full/ncomms4562.html
33 Mutant Cohesin in Premature Ovarian Failure.
http://www.nejm.org/doi/full/10.1056/NEJMoa1309635
32 Gaucher's disease is a lysosomal storage disease caused by mutations in the glucocerebrosidase gene. Now, Anthony Futerman and his colleagues report that the expression of proteins linked to a form of cell death called necroptosis is increased in Gaucher's disease and that blocking these proteins can improve disease in a mouse model.
http://www.nature.com/nm/journal/v20/n2/abs/nm.3449.html
31 A risk haplotype for type 2 diabetes is identified with four amino acid substitutions in SLC16A11, which is present at ~50% frequency in Native American samples and ~10% in east Asian samples, but is rare in European and African samples; SLC16A11 may alter hepatic lipid metabolism, causing an increase in triacylglycerol levels.
http://www.nature.com/nature/journal/v506/n7486/full/nature12828.html
30 Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)61134-4/abstract
29 Case report: Intradiscal oxygen ozone therapy in uncontained lumbar disc herniation.
http://f1000research.com/articles/1-13/v1
28 Management of acute and post-operative pain in chronic kidney disease.
http://f1000research.com/articles/2-28/v3
27 High-Content siRNA Screen Reveals Global ENaC Regulators and Potential Cystic Fibrosis Therapy Targets.
http://www.cell.com/abstract/S0092-8674(13)01076-3
26 Reprogramming of Intestinal Glucose Metabolism and Glycemic Control in Rats After Gastric Bypass.
http://www.sciencemag.org/content/341/6144/406.abstract
25 Inositol kinase and its product accelerate wound healing by modulating calcium levels, Rho GTPases, and F-actin assembly.
http://www.pnas.org/content/110/27/11029.abstract
24 A mouse model of adult-onset anaemia due to erythropoietin deficiency.
http://www.nature.com/ncomms/2013/130603/ncomms2950/full/ncomms2950.html
23 In vivo minimally invasive interstitial multi-functional microendoscopy.
http://www.nature.com/srep/2013/130528/srep01805/full/srep01805.html
22 Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trial.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)60250-0/abstract
21 Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension.
http://www.nature.com/ng/journal/v45/n5/abs/ng.2581.html
20 Laser Welding of Ruptured Intestinal Tissue Using Plasmonic Polypeptide Nanocomposite Solders.
http://pubs.acs.org/doi/abs/10.1021/nn303202k
19 Bundles of Spider Silk, Braided into Sutures, Resist Basic Cyclic Tests: Potential Use for Flexor Tendon Repair.
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0061100
18 Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy.
http://www.nature.com/nm/journal/v19/n4/abs/nm.3092.html
17 Proteoglycan 4 protects from age-related and posttraumatic osteoarthritis development.
http://stm.sciencemag.org/content/5/176/176ra34.abstract
16 Rescue of hearing and vestibular function by antisense oligonucleotides in a mouse model of human deafness.
http://www.nature.com/nm/journal/v19/n3/abs/nm.3106.html
15 Increased carbamylation of serum albumin is associated with increased mortality in patients with kidney failure.
http://stm.sciencemag.org/content/5/175/175ra29.abstract
14 Minimal Intensity Physical Activity (Standing and Walking) of Longer Duration Improves Insulin Action and Plasma Lipids More than Shorter Periods of Moderate to Vigorous Exercise (Cycling) in Sedentary Subjects When Energy Expenditure Is Comparable.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0055542
13 Towards germline gene therapy of inherited mitochondrial diseases.
http://www.nature.com/nature/journal/v493/n7434/full/nature11647.html
12 Human Cartilage Repair with a Photoreactive Adhesive-Hydrogel Composite.
http://stm.sciencemag.org/content/5/167/167ra6.abstract
11 Carbon-Nanotube Optoacoustic Lens for Focused Ultrasound Generation and High-Precision Targeted Therapy.
http://www.nature.com/srep/2012/121218/srep00989/full/srep00989.html
10 Genetic Correction of Human Induced Pluripotent Stem Cells from Patients with Spinal Muscular Atrophy.
http://stm.sciencemag.org/content/4/165/165ra162.abstract
9 The 21st century hazards of smoking and benefits of stopping: a prospective study of one million women in the UK.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)61720-6/fulltext
8 A New Body Shape Index Predicts Mortality Hazard Independently of Body Mass Index.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0039504
7 Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors.
http://www.nature.com/nm/journal/v18/n9/abs/nm.2891.html
6 Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)61031-9/fulltext
5 Nucleic acid scavengers inhibit thrombosis without increasing bleeding.
http://www.pnas.org/content/109/32/12938.abstract
4 Mucus Penetrating Nanoparticles: Biophysical Tool and Method of Drug and Gene Delivery.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201201800/abstract
3 X-Space MPI: Magnetic Nanoparticles for Safe Medical Imaging.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201200221/abstract
2 Noninvasive in vivo optical detection of biofilm in the human middle ear.
http://www.pnas.org/content/109/24/9529.abstract
1 Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes.
http://www.cell.com/abstract/S0092-8674(12)00166-3
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