74 Association of Electronic Cigarette Use With Initiation of Combustible Tobacco Product Smoking in Early Adolescence.
http://jama.jamanetwork.com/article.aspx?articleid=2428954
73 p75NTR-dependent activation of NF-κB regulates microRNA-503 transcription and pericyte–endothelial crosstalk in diabetes after limb ischaemia.
http://www.nature.com/ncomms/2015/150813/ncomms9024/full/ncomms9024.html
72 Twentieth century surge of excess adult male mortality.
http://www.pnas.org/content/112/29/8993.abstract
71 Secukinumab, a human anti-interleukin-17A monoclonal antibody, in patients with psoriatic arthritis.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(15)61134-5/abstract
70 Small bites versus large bites for closure of abdominal midline incisions (STITCH).
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(15)60459-7/abstract
69 Trial of a Paclitaxel-Coated Balloon for Femoropopliteal Artery Disease.
http://www.nejm.org/doi/full/10.1056/NEJMoa1406235
68 Lumacaftor–Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR.
http://www.nejm.org/doi/full/10.1056/NEJMoa1409547
67 A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management.
http://www.nejm.org/doi/full/10.1056/NEJMoa1411892
66 Tmc gene therapy restores auditory function in deaf mice.
http://stm.sciencemag.org/content/7/295/295ra108
65 Allergen-Induced Asthmatic Responses Modified by a GATA3-Specific DNAzyme.
http://www.nejm.org/doi/full/10.1056/NEJMoa1411776
64 Large-scale serum protein biomarker discovery in Duchenne muscular dystrophy.
http://www.pnas.org/content/112/23/7153.abstract
63 Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients.
http://stm.sciencemag.org/content/7/290/290ra87
62 Targeting joint-lining fibroblast-like synoviocytes reduces the severity of arthritis.
http://stm.sciencemag.org/content/7/288/288ra76.abstract
61 Prolonged exposure to acetaminophen reduces testosterone production by the human fetal testis in a xenograft model.
http://stm.sciencemag.org/content/7/288/288ra80
60 Risk of serious infection in biological treatment of patients with rheumatoid arthritis: a systematic review and meta-analysis.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(14)61704-9/abstract
59 Intensive Diabetes Therapy and Ocular Surgery in Type 1 Diabetes.
http://www.nejm.org/doi/full/10.1056/NEJMoa1409463
58 Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life.
http://www.cell.com/cell-host-microbe/abstract/S1931-3128(15)00162-6
57 Widespread seasonal gene expression reveals annual differences in human immunity and physiology.
http://www.nature.com/ncomms/2015/150512/ncomms8000/full/ncomms8000.html
56 Induction of labour versus expectant management for large-for-date fetuses: a randomised controlled trial.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(14)61904-8/abstract
55 Efficacy of idebenone on respiratory function in patients with Duchenne muscular dystrophy not using glucocorticoids (DELOS): a double-blind randomised placebo-controlled phase 3 trial.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(15)60025-3/abstract
54 School-based suicide prevention programmes: the SEYLE cluster-randomised, controlled trial.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(14)61213-7/fulltext
53 Central arteriovenous anastomosis for the treatment of patients with uncontrolled hypertension (the ROX CONTROL HTN study): a randomised controlled trial.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(14)62053-5/fulltext
52 Cell-free DNA Analysis for Noninvasive Examination of Trisomy.
http://www.nejm.org/doi/full/10.1056/NEJMoa1407349
51 Impedance sensing device enables early detection of pressure ulcers in vivo.
http://www.nature.com/ncomms/2015/150317/ncomms7575/full/ncomms7575.html
50 Large-scale discovery of novel genetic causes of developmental disorders.
http://www.nature.com/nature/journal/v519/n7542/full/nature14135.html
49 Smoking is associated with mosaic loss of chromosome Y.
http://www.sciencemag.org/content/347/6217/81.abstract
48 Cytisine versus Nicotine for Smoking Cessation.
http://www.nejm.org/doi/full/10.1056/NEJMoa1407764
47 A Wnt-TGFβ2 axis induces a fibrogenic program in muscle stem cells from dystrophic mice.
http://stm.sciencemag.org/content/6/267/267ra176
46 Affinity-based design of a synthetic universal reversal agent for heparin anticoagulants.
http://stm.sciencemag.org/content/6/260/260ra150
45 Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function.
http://stke.sciencemag.org/content/7/347/ra97.abstract
44 A Modified γ-Retrovirus Vector for X-Linked Severe Combined Immunodeficiency.
http://www.nejm.org/doi/full/10.1056/NEJMoa1404588
43 Immunomodulation with eicosapentaenoic acid supports the treatment of autoimmune small-vessel vasculitis.
http://www.nature.com/srep/2014/140918/srep06406/full/srep06406.html
42 Treatment of heterotopic ossification through remote ATP hydrolysis.
http://stm.sciencemag.org/content/6/255/255ra132.abstract
41 A plasmonic chip for biomarker discovery and diagnosis of type 1 diabetes.
http://www.nature.com/nm/journal/v20/n8/abs/nm.3619.html
40 Supercooling enables long-term transplantation survival following 4 days of liver preservation.
http://www.nature.com/nm/journal/v20/n7/abs/nm.3588.html
39 Intravenously administered nanoparticles increase survival following blast trauma.
http://www.pnas.org/content/111/28/10293.abstract
38 Letrozole versus Clomiphene for Infertility in the Polycystic Ovary Syndrome.
http://www.nejm.org/doi/full/10.1056/NEJMoa1313517
37 Pasireotide for Postoperative Pancreatic Fistula.
http://www.nejm.org/doi/full/10.1056/NEJMoa1313688
36 Characterizing asthma from a drop of blood using neutrophil chemotaxis.
http://www.pnas.org/content/111/16/5813.abstract
35 Close-Field Electroporation Gene Delivery Using the Cochlear Implant Electrode Array Enhances the Bionic Ear.
http://stm.sciencemag.org/content/6/233/233ra54
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