169 Structure of the human dopamine transporter and mechanisms of inhibition
https://www.nature.com/articles/s41586-024-07739-9
168 Molecular mechanism of ligand gating and opening of NMDA receptor
https://www.nature.com/articles/s41586-024-07742-0
167 De novo design of luciferases using deep learning.
https://www.nature.com/articles/s41586-023-05696-3
166 Structure-based design of bitopic ligands for the µ-opioid receptor.
https://www.nature.com/articles/s41586-022-05588-y
165 Structures of the entire human opioid receptor family.
https://www.cell.com/cell/fulltext/S0092-8674(22)01545-8
164 Mapping the Accessory Proteins (Orfs) of Severe Acute Respiratory Syndrome Coronavirus 2.
https://www.liebertpub.com/doi/10.1089/regen.2022.0056
163 Geometric deep learning of RNA structure.
http://science.sciencemag.org/content/373/6558/1047
162 Computational design of a synthetic PD-1 agonist.
https://www.pnas.org/content/118/29/e2102164118
161 Structural basis of omega-3 fatty acid transport across the blood–brain barrier.
https://www.nature.com/articles/s41586-021-03650-9
160 A structure of RNA polymerase II in complex with spliceosomal particle U1 snRNP reveals how transcription and RNA splicing are coupled.
https://science.sciencemag.org/content/371/6526/305
159 Structures of the iron transporter ferroportin and the peptide hormone hepcidin suggest how iron homeostasis is tightly regulated.
https://www.nature.com/articles/s41586-020-2668-z
158 Computational design of transmembrane pores.
https://www.nature.com/articles/s41586-020-2646-5
157 Structures of human pannexin 1 reveal ion pathways and mechanism of gating.
https://www.nature.com/articles/s41586-020-2357-y
156 A mass spectrometry analysis reveals the glycan composition at all glycosylation sites on the SARS-CoV-2 spike protein.
https://science.sciencemag.org/content/369/6501/330
155 Structure of the RNA-dependent RNA polymerase from COVID-19 virus.
https://science.sciencemag.org/content/368/6492/779
154 The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage.
https://www.pnas.org/content/117/19/10254
153 The Structure of the Membrane Protein of SARS-CoV-2 Resembles the Sugar Transporter semiSWEET.
https://www.preprints.org/manuscript/202004.0512/v1
152 Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors.
https://science.sciencemag.org/content/368/6489/409
151 Structure of mouse coronavirus spike protein complexed with receptor reveals mechanism for viral entry.
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1008392
150 Structural insight into arenavirus replication machinery.
https://www.nature.com/articles/s41586-020-2114-2
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