6 Palmitoylation influences the function and pharmacology of sodium channels.
http://www.pnas.org/content/108/50/20213.abstract
5 Targeted killing of a mammalian cell based upon its specialized metabolic state. Alexander PB. et al. (2011). PNAS 108: 15828-15833.
http://www.pnas.org/content/108/38/15828.abstract
4 Subcutaneous administration of leptin normalizes fasting plasma glucose in obese type 2 diabetic UCD-T2DM rats. Cummings BP. et al. (2011). PNAS 108:14670-14675.
http://www.pnas.org/content/108/35/14670.abstract
3 Hydrogen is an energy source for hydrothermal vent symbioses. Petersen JM. et al. (2011). Nature 476:176-180.
http://www.nature.com/nature/journal/v476/n7359/full/nature10325.html
2 Hypothalamic insulin resistance is induced by dietary fat by activating inflammatory signals which in turn stimulates food intake.
Posey et al. (2009) Am J Physiol Endocrinol Metab 296: E1003-E1012.
http://ajpendo.physiology.org/cgi/reprint/296/5/E1003
1 Fibroblast growth factor-21(FGF-21) induces peroxisome proliferator-activated receptor gamma coactivator protein-1alpha modulating flux through fat oxidation, TCA cycle and gluconeogenesis. FGF-21 regulates carbohydrate and fat metabolism during the fasting to starvation phase. Potthoff et al. (2009) Proc Natl Acad Sci 106(26):10853-10858.
http://www.pnas.org/content/106/26/10853.full.pdf+html
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