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Molecular Biology

Molecular Biology

Articles:

31  Mitochondrial reactive oxygen species drive proinflammatory cytokine production. Naik E and Dixit VM. (2011). J. Exp. Med. 208: 417-420.
http://jem.rupress.org/content/208/3/417.abstract

30  Cardiac myosin activation: A potential therapeutic approach for systolic heart failure. Malik FI. et al. (2011). Science 331:1439-1443.
http://www.sciencemag.org/content/331/6023/1439.abstract

29  Direct interaction of RNA polymerase II and mediator required for transcription in vivo. Soutourina J. et al. (2011). Science 331:1451-1454.
http://www.sciencemag.org/content/331/6023/1451.abstract

28  Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma. Keunen O et al. (2011). PNAS 108: 3749-3754.
http://www.pnas.org/content/108/9/3749.abstract

27  Messenger RNA has received little attention as a potential therapeutic agent. Kormann et al. show that intramuscular injection of chemically modified erythropoietin mRNA substantially increases the hematocrit in mice and demonstrate the curative potential of pulmonary mRNA delivery in a mouse model of congenital surfactant protein B deficiency. Kormann SD et al. (2011). Nature Biotechnology 29: 154–157
http://www.nature.com/nbt/journal/v29/n2/abs/nbt.1733.html

26  miR-34a regulates progenitor and metastatic properties of prostate cancer cells, and they identify CD44 as a relevant target of the microRNA. The inhibition of metastasis observed after systemic delivery of miR-34a suggests that it could be used as a potential therapeutic agent in prostate cancer. Liu et al. (2011). Nature Medicine 17:211–215
http://www.nature.com/nm/journal/v17/n2/abs/nm.2284.html

25  Identification of aneuploidy-selective antiproliferation compounds. Tang Y-C, et al. (2011). Cell 144:499-512.
http://www.cell.com/abstract/S0092-8674(11)00056-0

24  Cells respond to mechanical stress by rapid disassembly of caveolae. Sinha B. et al. (2011). Cell 144: 402-413.
http://www.cell.com/abstract/S0092-8674(10)01523-0

23  Mutant proteins as cancer-specific biomarkers. Wang Q, et al. (2011). PNAS 108:2444-2449.
http://www.pnas.org/content/108/6/2444.abstract

22  Multistage nanoparticle delivery system for deep penetration into tumor tissue. Wong C. et al. (2011). PNAS 108:2426-2431.
http://www.pnas.org/content/108/6/2426.abstract

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