271 Mutants of Cre recombinase with improved accuracy.
http://www.nature.com/ncomms/2013/130923/ncomms3509/full/ncomms3509.html
270 Postnatal Soluble FGFR3 Therapy Rescues Achondroplasia Symptoms and Restores Bone Growth in Mice.
http://stm.sciencemag.org/content/5/203/203ra124.abstract
269 Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
http://www.pnas.org/content/110/38/15180.abstract
268 High-resolution three-dimensional mapping of mRNA export through the nuclear pore.
http://www.nature.com/ncomms/2013/130906/ncomms3414/full/ncomms3414.html
267 Autophagy, which is believed to be an Atg7- and Atg3-dependent process, is known to be involved in animal development. Baehrecke and colleagues show that autophagy drives the controlled degradation of the developing Drosophila midgut. Interestingly, this process is Atg7- and Atg3-independent, and instead requires the E1-activating enzyme Uba1 for programmed reduction of cell size in the midgut.
http://www.nature.com/ncb/journal/v15/n9/abs/ncb2804.html
266 Histone modification controls mammalian sex determination.
http://www.sciencemag.org/content/341/6150/1106.abstract
265 The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein.
http://www.nature.com/nature/journal/v501/n7465/full/nature12402.html
264 From Structure to Systems: High-Resolution, Quantitative Genetic Analysis of RNA Polymerase II.
http://www.cell.com/abstract/S0092-8674(13)00938-0
263 Induction of autophagy is coupled to reduction of histone H4 lysine 16 acetylation through downregulation of the histone acetyltransferase hMOF, showing that histone modifications regulate the outcome of autophagy.
http://www.nature.com/nature/journal/v500/n7463/full/nature12313.html
262 A Long Noncoding RNA Mediates Both Activation and Repression of Immune Response Genes.
http://www.sciencemag.org/content/341/6147/789.abstract
|