Molecular Biology


483  The RNA polymerase clamp closes to initiate promoter melting, opens to load melted DNA, and closes again for a tight grip on DNA.

482  Visualizing multistep elevator-like transitions of a nucleoside transporter.

481  A mouse tissue transcription factor atlas.

480  CRISPR-Cpf1 correction of muscular dystrophy mutations in human cardiomyocytes and mice.

479  CRISPR–Cas systems exploit viral DNA injection to establish and maintain adaptive immunity.

478  Light-sensing via hydrogen peroxide and a peroxiredoxin.

477  Self-assembly of genetically encoded DNA-protein hybrid nanoscale shapes.

476  RNA m6A methylation regulates the ultraviolet-induced DNA damage response.

475  A technique called genome architecture mapping (GAM) involves sequencing DNA from a large number of thin nuclear cryosections to develop a map of genome organization without the limitations of existing 3C-based methods.

474  Deep-sea vent phage DNA polymerase specifically initiates DNA synthesis in the absence of primers.

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