Molecular Biology

Articles:

506  Identification of an ion channel that functions in sour taste sensation in mammals and flies is described.
http://science.sciencemag.org/content/359/6379/1047

505  Cryo-electron microscopy and single-molecule studies reveal that the adaptors BICDR1 and HOOK3 recruit two dynein molecules to dynactin and thereby increase the force and speed of the dynein–dynactin microtubule motor.
https://www.nature.com/articles/nature25462

504  Structure of the yeast oligosaccharyltransferase complex gives insight into eukaryotic N-glycosylation.
http://science.sciencemag.org/content/359/6375/545

503  DNA synthesis from diphosphate substrates by DNA polymerases.
http://www.pnas.org/content/115/5/980

502  Dicer uses distinct modules for recognizing dsRNA termini.
http://science.sciencemag.org/content/359/6373/329

501  The retrotransposition of L1 is controlled by functionally diverse genes at the transcriptional or post-transcriptional levels, and its silencing can lead to the downregulation of host gene expression.
https://www.nature.com/articles/nature25179

500  Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents.
https://www.nature.com/articles/nature25164

499  An RNA-editing technology is developed to efficiently and specifically deplete and correct RNA directly in mammalian cells.
http://science.sciencemag.org/content/358/6366/1019

498  Charged residues in the H-NS linker drive DNA binding and gene silencing in single cells.
http://www.pnas.org/content/114/47/12560.abstract

497  Generation of specific inhibitors of SUMO-1– and SUMO-2/3–mediated protein-protein interactions using Affimer (Adhiron) technology.
http://stke.sciencemag.org/content/10/505/eaaj2005

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