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Cancer Biology

Cancer Biology

 
174 Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer.
http://www.nature.com/nature/journal/v493/n7432/full/nature11725.html

173 Sickle Erythrocytes Target Cytotoxics to Hypoxic Tumor Microvessels and Potentiate a Tumoricidal Response.
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0052543

172 An Inhibitor of Nonhomologous End-Joining Abrogates Double-Strand Break Repair and Impedes Cancer Progression.
http://www.cell.com/abstract/S0092-8674(12)01489-4

171 Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation.
http://www.pnas.org/content/109/52/21360.abstract

170 Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan.
http://www.nature.com/ncb/journal/v15/n1/abs/ncb2643.html

169 Tregs that expand in human colon cancer have proinflammatory properties and contribute to tumor progression.
http://stm.sciencemag.org/content/4/164/164ra159.abstract

168 A magnetic switch for the control of cell death signalling in in vitro and in vivo systems.
http://www.nature.com/nmat/journal/v11/n12/full/nmat3430.html

167 Blocking the activation of p110β by G proteins inhibits tumor cell proliferation.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;5/253/ra89

166 Mice Lacking a Myc Enhancer That Includes Human SNP rs6983267 Are Resistant to Intestinal Tumors.
http://www.sciencemag.org/content/338/6112/1360.abstract

165 Combination of glycolysis inhibition with chemotherapy results in an antitumor immune response.
http://www.pnas.org/content/109/49/20071.abstract

164 Cancer resistance in the blind mole rat is mediated by concerted necrotic cell death mechanism.
http://www.pnas.org/content/109/47/19392.abstract

163 Loss of the Par3 Polarity Protein Promotes Breast Tumorigenesis and Metastasis.
http://www.cell.com/cancer-cell/abstract/S1535-6108(12)00437-0

162 Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth.
http://www.cell.com/cancer-cell/abstract/S1535-6108(12)00398-4

161 An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background.
http://www.nature.com/nature/journal/v491/n7424/full/nature11624.html

160 Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes.
http://www.nature.com/nature/journal/v491/n7424/full/nature11547.html

159 Variant Ciz1 is a circulating biomarker for early-stage lung cancer.
http://www.pnas.org/content/109/45/E3128.abstract

158 Genetic ablation or pharmacological inhibition of a lipid signaling enzyme attenuates tumor growth and metastasis.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;5/249/ra79

157 PDK1 in the nucleus drives oncogenesis in mice and correlates with human prostate tumor grade.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;5/249/ra80

156 In Vitro and In Vivo Near-Infrared Photothermal Therapy of Cancer Using Polypyrrole Organic Nanoparticles.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201202625/abstract

155 A cell-penetrating lupus anti-DNA antibody inhibits DNA repair, sensitizes cancer cells to DNA-damaging therapy in vitro and in vivo, and is synthetically lethal to BRCA2-deficient human cancer cells.
http://stm.sciencemag.org/content/4/157/157ra142.abstract

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