194 Vitamin E suppresses the proliferation of prostate cancer cells by inhibiting the growth-promoting kinase Akt.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;6/267/ra19
193 A therapeutic monoclonal antibody specific for the intracellular oncoprotein Wilms tumor 1 treats human leukemias in mice.
http://stm.sciencemag.org/content/5/176/176ra33.abstract
192 Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling.
http://www.pnas.org/content/110/11/E1026.abstract
191 Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche.
http://www.nature.com/nature/journal/v495/n7440/full/nature11979.html
190 Wang and colleagues show that miR-126 and miR-126* suppress metastasis by inhibiting the production of the Sdf-1α cytokine in mouse mammary tumours, resulting in decreased recruitment of mesenchymal stem cells and inflammatory monocytes to the tumour stroma.
http://www.nature.com/ncb/journal/v15/n3/abs/ncb2690.html
189 Dopamine-Melanin Colloidal Nanospheres: An Efficient Near-Infrared Photothermal Therapeutic Agent for In Vivo Cancer Therapy.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201204683/abstract
188 Xist RNA Is a Potent Suppressor of Hematologic Cancer in Mice.
http://www.cell.com/abstract/S0092-8674(13)00086-X
187 Cloaking nanoparticles with host-like peptides increases their lifetime enough to allow imaging of tumors.
http://www.sciencemag.org/content/339/6122/971.abstract
186 Conjugated Polymer-Coated Bacteria for Multimodal Intracellular and Extracellular Anticancer Activity.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201204550/abstract
185 Carbohydrate-based vaccines with a glycolipid adjuvant for breast cancer.
http://www.pnas.org/content/110/7/2517.abstract
184 Werb and colleagues demonstrate that GATA3, a transcription factor that promotes luminal differentiation in the mammary gland, suppresses breast cancer metastasis to the lung by upregulating miR-29b. This microRNA suppresses pro-metastatic characteristics, including mesenchymal traits and the expression of microenvironmental factors involved in angiogenesis and extracellular matrix remodelling.
http://www.nature.com/ncb/journal/v15/n2/abs/ncb2672.html
183 Muthuswamy and colleagues demonstrated that loss of the Par3 polarity protein cooperates with ErbB2 activity to promote cell invasion and metastasis by destabilizing E-cadherin-dependent cell–cell junctions.
http://www.nature.com/ncb/journal/v15/n2/abs/ncb2663.html
182 Engineering a BCR-ABL–activated caspase for the selective elimination of leukemic cells.
http://www.pnas.org/content/110/6/2300.abstract
181 Drug resistance in melanomas may be overcome by therapies that trigger endoplasmic reticulum stress.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;6/260/ra7
180 Tumor cells circulating in the blood of cancer patients undergo a phenotypic change that may facilitate their spread.
http://www.sciencemag.org/content/339/6119/580.abstract
179 Nanoroughened Surfaces for Efficient Capture of Circulating Tumor Cells without Using Capture Antibodies.
http://pubs.acs.org/doi/abs/10.1021/nn304719q
178 Antitumor activity of a pyrrole-imidazole polyamide.
http://www.pnas.org/content/110/5/1863.abstract
177 Inhibition of triple-negative breast cancer models by combinations of antibodies to EGFR.
http://www.pnas.org/content/110/5/1815.abstract
176 Smg1 haploinsufficiency predisposes to tumor formation and inflammation.
http://www.pnas.org/content/110/4/E285.abstract
175 Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth.
http://www.pnas.org/content/110/3/972.abstract
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