414 Nanoparticle-formulated siRNA targeting integrins inhibits hepatocellular carcinoma progression in mice.
http://www.nature.com/ncomms/2014/140521/ncomms4869/full/ncomms4869.html
413 A Long Noncoding RNA Activated by TGF-β Promotes the Invasion-Metastasis Cascade in Hepatocellular Carcinoma.
http://www.cell.com/cancer-cell/abstract/S1535-6108(14)00119-6
412 γδT17 Cells Promote the Accumulation and Expansion of Myeloid-Derived Suppressor Cells in Human Colorectal Cancer.
http://www.cell.com/immunity/abstract/S1074-7613(14)00147-2
411 Targeting Lactate Dehydrogenase-A Inhibits Tumorigenesis and Tumor Progression in Mouse Models of Lung Cancer and Impacts Tumor-Initiating Cells.
http://www.cell.com/cell-metabolism/abstract/S1550-4131(14)00107-7
410 A Nanoparticle-Based Combination Chemotherapy Delivery System for Enhanced Tumor Killing by Dynamic Rewiring of Signaling Pathways.
http://stke.sciencemag.org/cgi/content/abstract/7/325/ra44
409 An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging.
http://www.nature.com/ncomms/2014/140515/ncomms4626/full/ncomms4626.html
408 An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage.
http://www.nature.com/nm/journal/v20/n5/abs/nm.3519.html
407 T cells specific for a mutation expressed by tumor cells show antitumor activity in a patient with an epithelial cancer.
http://www.sciencemag.org/content/344/6184/641.abstract
406 S100A11 is required for efficient plasma membrane repair and survival of invasive cancer cells.
http://www.nature.com/ncomms/2014/140508/ncomms4795/full/ncomms4795.html
405 Hypermutable DNA chronicles the evolution of human colon cancer.
http://www.pnas.org/content/111/18/E1889.abstract
404 Understanding how inhibitors rewire the Met receptor pathway points to a strategy for more effective gastric cancer treatment.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;7/322/ra38
403 Bcl2L13 is a ceramide synthase inhibitor in glioblastoma.
http://www.pnas.org/content/111/15/5682.abstract
402 T helper 17 cells play a critical pathogenic role in lung cancer.
http://www.pnas.org/content/111/15/5664.abstract
401 Targeted In Vivo Imaging of Microscopic Tumors with Ferritin-based Nanoprobes Across Biological Barriers.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201304544/abstract
400 Oncogenic microRNA-3151 interferes with the p53-mediated apoptosis pathway to produce more severe leukemia.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;7/321/ra36
399 Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy.
http://www.nature.com/nature/journal/v508/n7495/full/nature13194.html
398 MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.
http://www.nature.com/nature/journal/v508/n7495/full/nature13181.html
397 The delivery of therapeutics using an external trigger is an attractive route for the improvement of targeted disease treatment. Here, the authors have discovered a porphyrin–phospholipid liposome for light-controlled membrane permeabilization and use the system to deliver an anticancer drug in vivo.
http://www.nature.com/ncomms/2014/140403/ncomms4546/full/ncomms4546.html
396 Triple-negative breast cancers (TNBC) show an increased basal level of endoplasmic reticulum stress and activation of the XBP1 branch of the unfolded protein response; furthermore, XBP1 promotes tumour formation of TNBC cell lines by interacting with and regulating HIF1α.
http://www.nature.com/nature/journal/v508/n7494/full/nature13119.html
395 Arginine Starvation Impairs Mitochondrial Respiratory Function in ASS1-Deficient Breast Cancer Cells.
http://stke.sciencemag.org/cgi/content/abstract/7/319/ra31
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