534 A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis.
http://www.nature.com/nature/journal/v520/n7547/full/nature14403.html
533 Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer.
http://www.nature.com/nature/journal/v520/n7547/full/nature14292.html
532 Postsurgical adjuvant or metastatic renal cell carcinoma therapy models reveal potent antitumor activity of metronomic oral topotecan with pazopanib.
http://stm.sciencemag.org/content/7/282/282ra50
531 A humanized mouse model facilitates the identification of T cell receptors for unmutated cancer antigens.
http://www.nature.com/nbt/journal/v33/n4/abs/nbt.3147.html
530 Soluble proteins shed by tumors stimulate natural killer cell–mediated antitumor immunity in mice.
http://www.sciencemag.org/content/348/6230/136.abstract
529 An anticancer drug is more effective against tumors that carry more mutations.
http://www.sciencemag.org/content/348/6230/124.abstract
528 Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells.
http://www.pnas.org/content/112/13/4086.abstract
527 The nuclear translocation of ERK1/2 as an anticancer target.
http://www.nature.com/ncomms/2015/150330/ncomms7685/full/ncomms7685.html
526 Transfer hydrogenation catalysis in cells as a new approach to anticancer drug design.
http://www.nature.com/ncomms/2015/150320/ncomms7582/full/ncomms7582.html
525 Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAFV600E melanoma.
http://stm.sciencemag.org/content/7/279/279ra41
524 Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients.
http://www.nature.com/nature/journal/v519/n7543/full/nature14320.html
523 Quorum-sensing Salmonella selectively trigger protein expression within tumors.
http://www.pnas.org/content/112/11/3457.abstract
522 Sensitive β-galactosidase-targeting fluorescence probe for visualizing small peritoneal metastatic tumours in vivo.
http://www.nature.com/ncomms/2015/150313/ncomms7463/full/ncomms7463.html
521 A comprehensive transcriptional portrait of human cancer cell lines.
http://www.nature.com/nbt/journal/v33/n3/abs/nbt.3080.html
520 Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis.
http://www.nature.com/ncb/journal/v17/n3/abs/ncb3110.html
519 A gp130–Src–YAP module links inflammation to epithelial regeneration.
http://www.nature.com/nature/journal/v519/n7541/full/nature14228.html
518 Whole genomes redefine the mutational landscape of pancreatic cancer.
http://www.nature.com/nature/journal/v518/n7540/full/nature14169.html
517 Telomerase reverse transcriptase promoter mutations can cause high-level reactivation of the telomerase enzyme in bladder cancer.
http://www.sciencemag.org/content/347/6225/1006.abstract
516 A chimeric antigen receptor redirects T cells to treat glioblastoma.
http://stm.sciencemag.org/content/7/275/275ra22.abstract
515 A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice.
http://www.sciencemag.org/content/347/6223/779.abstract
|