554 Active targeting of chemotherapy to disseminated tumors using nanoparticle-carrying T cells.
http://stm.sciencemag.org/content/7/291/291ra94
553 Combining three antibodies nullifies feedback-mediated resistance to erlotinib in lung cancer.
http://stke.sciencemag.org/content/8/379/ra53.abstract
552 α-Enolase–targeted lipid nanoparticles containing chemotherapeutic drugs are effective for the treatment of colorectal cancer.
http://stm.sciencemag.org/content/7/290/290ra91.abstract
551 An “organelle knockout” strategy reveals that cancer cells but not normal cells can divide in the absence of centrosomes.
http://www.sciencemag.org/content/348/6239/1155.abstract
550 The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase.
http://www.nature.com/nature/journal/v522/n7554/full/nature14492.html
549 Probiotics programmed to generate specific metabolites traffic from the gut to tumors and enable cancer detection through the urine.
http://stm.sciencemag.org/content/7/289/289ra84.abstract
548 A CD3xCD123 bispecific DART for redirecting host T cells to myelogenous leukemia: Preclinical activity and safety in nonhuman primates.
http://stm.sciencemag.org/content/7/289/289ra82
547 Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma.
http://jco.ascopubs.org/content/early/2015/05/22/JCO.2014.58.3377.abstract?sid=25367564-a56b-46d4-b1d0-c0af42ba0d65
546 Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth.
http://www.nature.com/ncomms/2015/150526/ncomms8215/full/ncomms8215.html
545 Marrow-infiltrating lymphocytes (MILs) may be used as adoptive cell therapy for multiple myeloma.
http://stm.sciencemag.org/content/7/288/288ra78.abstract
544 Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia.
http://www.nature.com/ni/journal/vaop/ncurrent/full/ni.3160.html
543 A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells.
http://www.sciencemag.org/content/348/6236/803.abstract
542 Inhibition of vemurafenib-resistant melanoma by interference with pre-mRNA splicing.
http://www.nature.com/ncomms/2015/150514/ncomms8103/full/ncomms8103.html
541 Noninvasive imaging of immune responses.
http://www.pnas.org/content/112/19/6146
540 SoNar, a Highly Responsive NAD+/NADH Sensor, Allows High-Throughput Metabolic Screening of Anti-tumor Agents.
http://www.cell.com/cell-metabolism/abstract/S1550-4131(15)00164-3
539 ITIM-containing receptor LAIR1 supports self-renewal and survival of acute myeloid leukaemia stem cells through a signalling pathway that includes the SHP-1 phosphatase, CAMK1 kinase and CREB transcription factor.
http://www.nature.com/ncb/journal/v17/n5/abs/ncb3158.html
538 Two susceptibility loci identified for prostate cancer aggressiveness.
http://www.nature.com/ncomms/2015/150420/ncomms7889/full/ncomms7889.html
537 Sequential cancer mutations in cultured human intestinal stem cells.
http://www.nature.com/nature/journal/v521/n7550/full/nature14415.html
536 Mutant MHC class II epitopes drive therapeutic immune responses to cancer.
http://www.nature.com/nature/journal/v520/n7549/full/nature14426.html
535 Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo.
http://stm.sciencemag.org/content/7/284/284ra56
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