674 Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells.
http://www.nature.com/nature/journal/v534/n7607/full/nature18288.html
673 The metabolic co-regulator PGC1α suppresses prostate cancer metastasis.
http://www.nature.com/ncb/journal/v18/n6/abs/ncb3357.html
672 T cells from healthy human donors may be an important resource for outsourcing cancer immunotherapy.
http://science.sciencemag.org/content/352/6291/1337.abstract
671 SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b.
http://www.cell.com/cell/fulltext/S0092-8674(16)30476-7
670 Blockage of neddylation modification stimulates tumor sphere formation in vitro and stem cell differentiation and wound healing in vivo.
http://www.pnas.org/content/113/21/E2935.abstract
669 Design of a small molecule against an oncogenic noncoding RNA.
http://www.pnas.org/content/113/21/5898.abstract
668 Dormant breast cancer micrometastases reside in specific bone marrow niches that regulate their transit to and from bone.
http://stm.sciencemag.org/content/8/340/340ra73.abstract
667 The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia.
http://stm.sciencemag.org/content/8/339/339ra69.abstract
666 Activation of concurrent apoptosis and necroptosis by SMAC mimetics for the treatment of refractory and relapsed ALL.
http://stm.sciencemag.org/content/8/339/339ra70.abstract
665 Brain tumors can acquire resistance to therapy through changes to their microenvironment.
http://science.sciencemag.org/content/352/6288/aad3018
664 The transcription factor FOXF1 promotes prostate cancer by stimulating the mitogen-activated protein kinase ERK5.
http://stke.sciencemag.org/content/9/427/ra48
663 Light-Activated Hypoxia-Responsive Nanocarriers for Enhanced Anticancer Therapy.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201505869/full
662 Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis.
http://www.nature.com/ncb/journal/v18/n5/abs/ncb3340.html
661 A method called PRISM rapidly identifies drug candidates that are effective against specific cancer cell lines.
http://www.nature.com/nbt/journal/v34/n4/abs/nbt.3460.html
660 An injectable nanoparticle generator enhances delivery of cancer therapeutics.
http://www.nature.com/nbt/journal/v34/n4/abs/nbt.3506.html
659 Cellular uptake and anticancer activity of carboxylated gallium corroles.
http://www.pnas.org/content/113/16/E2258.abstract
658 Reporter nanoparticle that monitors its anticancer efficacy in real time.
http://www.pnas.org/content/113/15/E2104.abstract
657 sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance.
http://www.nature.com/nature/journal/v532/n7598/full/nature17392.html
656 Therapeutic vaccination against HPV16 is effective with chemotherapy for advanced cervical cancer patients.
http://stm.sciencemag.org/content/8/334/334ra52.abstract
655 Antioxidant antidiabetic drugs may promote tumor metastasis.
http://stm.sciencemag.org/content/8/334/334ra51
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