694 Mechanism of inhibition of the tumor suppressor Patched by Sonic Hedgehog.
http://www.pnas.org/content/113/40/E5866.abstract
693 Integrative analyses reveal a long noncoding RNA-mediated sponge regulatory network in prostate cancer.
http://www.nature.com/articles/ncomms10982
692 70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer.
http://www.nejm.org/doi/full/10.1056/NEJMoa1602253
691 Ionic immune suppression within the tumour microenvironment limits T cell effector function.
http://www.nature.com/nature/journal/v537/n7621/full/nature19364.html
690 A PGC1α-mediated transcriptional axis suppresses melanoma metastasis.
http://www.nature.com/nature/journal/v537/n7620/full/nature19347.html
689 Precision glycocalyx editing as a strategy for cancer immunotherapy.
http://www.pnas.org/content/113/37/10304
688 Combined targeting of BCL-2 and BCR-ABL tyrosine kinase eradicates chronic myeloid leukemia stem cells.
http://stm.sciencemag.org/content/8/355/355ra117.abstract
687 A CD19 chimeric antigen receptor–modified T cell product with defined composition has potent antitumor activity.
http://stm.sciencemag.org/content/8/355/355ra116.abstract
686 G9a/RelB regulates self-renewal and function of colon-cancer-initiating cells by silencing Let-7b and activating the K-RAS/β-catenin pathway.
http://www.nature.com/ncb/journal/v18/n9/abs/ncb3395.html
685 Melanoma miRNA trafficking controls tumour primary niche formation.
http://www.nature.com/ncb/journal/v18/n9/abs/ncb3399.html
684 A single dividing cell population with imbalanced fate drives oesophageal tumour growth.
http://www.nature.com/ncb/journal/v18/n9/abs/ncb3400.html
683 TNIK inhibition abrogates colorectal cancer stemness.
http://www.nature.com/articles/ncomms12586
682 Pancreatic adenocarcinoma cells drive autophagy in tumour microenvironment-associated stellate cells, which release alanine that is used by the cancer cells as a carbon source for a variety of metabolic processes in an otherwise nutrient-poor environment.
http://www.nature.com/nature/journal/v536/n7617/full/nature19084.html
681 miR-579-3p controls melanoma progression and resistance to target therapy.
http://www.pnas.org/content/113/34/E5005.abstract
680 A recellularized human colon model identifies cancer driver genes.
http://www.nature.com/nbt/journal/v34/n8/abs/nbt.3586.html
679 Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis.
http://www.nature.com/articles/ncomms12365
678 Human and murine tumour cells induce programmed necrosis (necroptosis) of endothelial cells, which promotes tumour cell extravasation and metastasis.
http://www.nature.com/nature/journal/v536/n7615/full/nature19076.html
677 Tumor-derived circulating endothelial cell clusters in colorectal cancer.
http://stm.sciencemag.org/content/8/345/345ra89
676 Clinical trial of blood-brain barrier disruption by pulsed ultrasound.
http://stm.sciencemag.org/content/8/343/343re2
675 Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy.
http://www.nature.com/nature/journal/v534/n7607/full/nature18300.html
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