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Cancer Biology

Cancer Biology

 
1410 Divergent FOXA1 mutations drive prostate tumorigenesis and therapy-resistant cellular plasticity
https://www.science.org/doi/10.1126/science.adv2367

1409 Rewiring of cortical glucose metabolism fuels human brain cancer growth
https://www.nature.com/articles/s41586-025-09460-7

1408 The landscape of microbial associations in human cancer
https://www.science.org/doi/10.1126/scitranslmed.ads6166

1407 Macrophage TBK1 signaling drives the development and outgrowth of breast cancer brain metastasis
https://www.pnas.org/doi/10.1073/pnas.2420793122

1406 Fragmentation signatures in cancer patients resemble those of patients with vascular or autoimmune diseases
https://www.pnas.org/doi/10.1073/pnas.2426890122

1405 Taurine from tumour niche drives glycolysis to promote leukaemogenesis
https://www.nature.com/articles/s41586-025-09018-7

1404 Nerve-to-cancer transfer of mitochondria during cancer metastasis
https://www.nature.com/articles/s41586-025-09176-8

1403 Respiratory viral infections awaken metastatic breast cancer cells in lungs
https://www.nature.com/articles/s41586-025-09332-0

1402 Radiation-induced amphiregulin drives tumour metastasis
https://www.nature.com/articles/s41586-025-08994-0

1401 Systemic administration of an RNA binding and cell-penetrating antibody targets therapeutic RNA to multiple mouse models of cancer
https://www.science.org/doi/10.1126/scitranslmed.adk1868

1400 BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interaction
https://www.science.org/doi/10.1126/science.adq2004

1399 The Vps13-like protein BLTP2 regulates phosphatidylethanolamine levels to maintain plasma membrane fluidity and breast cancer aggressiveness
https://www.nature.com/articles/s41556-025-01672-3

1398 Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITCH
https://www.nature.com/articles/s41556-025-01689-8

1397 eIF4A controls translation of estrogen receptor alpha and is a therapeutic target in advanced breast cancer
https://www.pnas.org/doi/10.1073/pnas.2424286122

1396 A neomorphic protein interface catalyzes covalent inhibition of RASG12D aspartic acid in tumors
https://www.science.org/doi/10.1126/science.ads0239

1395 Serotonin transporter inhibits antitumor immunity through regulating the intratumoral serotonin axis
https://www.cell.com/cell/fulltext/S0092-8674(25)00502-1

1394 Fine structural design of 3βHSD1 inhibitors for prostate cancer therapy
https://www.pnas.org/doi/10.1073/pnas.2422267122

1393 Nerve-to-cancer transfer of mitochondria during cancer metastasis
https://www.nature.com/articles/s41586-025-09176-8

1392 Concurrent loss of the Y chromosome in cancer and T cells impacts outcome
https://www.nature.com/articles/s41586-025-09071-2

1391 Targeted apoptotic immune modulator for the treatment of metastatic EGFR-positive solid tumors
https://www.pnas.org/doi/10.1073/pnas.2500489122

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