60 Thyroid Hormone Inactivation in Gastrointestinal Stromal Tumors.
http://www.nejm.org/doi/full/10.1056/NEJMoa1308893
59 Multitarget Stool DNA Testing for Colorectal-Cancer Screening.
http://www.nejm.org/doi/full/10.1056/NEJMoa1311194
58 Obinutuzumab plus Chlorambucil in Patients with CLL and Coexisting Conditions.
http://www.nejm.org/doi/full/10.1056/NEJMoa1313984
57 PI3Kδ Inhibition by Idelalisib in Patients with Relapsed Indolent Lymphoma.
http://www.nejm.org/doi/full/10.1056/NEJMoa1314583
56 Idelalisib and Rituximab in Relapsed Chronic Lymphocytic Leukemia.
http://www.nejm.org/doi/full/10.1056/NEJMoa1315226
55 Radical Prostatectomy or Watchful Waiting in Early Prostate Cancer.
http://www.nejm.org/doi/full/10.1056/NEJMoa1311593
54 Improved Survival with Bevacizumab in Advanced Cervical Cancer.
http://www.nejm.org/doi/full/10.1056/NEJMoa1309748
53 CD19 CAR T cell therapy induces complete remissions in 88% of 16 adult patients with relapsed or refractory acute lymphoblastic leukemia.
http://stm.sciencemag.org/content/6/224/224ra25.abstract
52 Low-Intensity Therapy in Adults with Burkitt's Lymphoma.
http://www.nejm.org/doi/full/10.1056/NEJMoa1308392
51 Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation.
http://www.pnas.org/content/110/47/19059.abstract
50 Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine.
http://www.nejm.org/doi/full/10.1056/NEJMoa1304369
49 Autologous Transplantation as Consolidation for Aggressive Non-Hodgkin's Lymphoma.
http://www.nejm.org/doi/full/10.1056/NEJMoa1301077?query=featured_home
48 In patients with advanced chemotherapy-refractory mesothelioma, treatment with the anti-mesothelin immunotoxin SS1P and immunosuppression with pentostatin and cyclophosphamide resulted in marked and durable tumor regressions.
http://stm.sciencemag.org/content/5/208/208ra147.abstract
47 Switch of glycolysis to gluconeogenesis by dexamethasone for treatment of hepatocarcinoma.
http://www.nature.com/ncomms/2013/131022/ncomms3508/full/ncomms3508.html
46 Systems biology and targeted mass spectrometry were combined to develop and validate a blood-based protein classifier for pulmonary nodules.
http://stm.sciencemag.org/content/5/207/207ra142.abstract
45 Sporadic colon cancer murine models demonstrate the value of autoantibody detection for preclinical cancer diagnosis.
http://www.nature.com/srep/2013/131015/srep02938/full/srep02938.html
44 Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk.
http://www.nature.com/ng/journal/v45/n10/abs/ng.2733.html
43 Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia.
http://www.nejm.org/doi/full/10.1056/NEJMoa1215134
42 Diagnosis of tumors during tissue-conserving surgery with integrated autofluorescence and Raman scattering microscopy.
http://www.pnas.org/content/110/38/15189.abstract
41 Stimulated Raman scattering microscopy provides a rapid, label-free means of detecting tumor infiltration of brain tissue ex vivo and in vivo.
http://stm.sciencemag.org/content/5/201/201ra119.abstract
40 Neovascular structures in acute myeloid leukemia can be targeted using a cognate antibody fused to human interleukin-2.
http://stm.sciencemag.org/content/5/201/201ra118.abstract
39 Epidermal EGFR regulates skin inflammation and contributes to skin barrier function and host defense.
http://stm.sciencemag.org/content/5/199/199ra111.abstract
38 Metabolic imaging with hyperpolarized pyruvate was used to safely and noninvasively visualize prostate tumors in patients.
http://stm.sciencemag.org/content/5/198/198ra108.abstract
37 Effect of Acute Exercise on Prostate Cancer Cell Growth.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0067579
36 A mass spectrometric approach was developed for intraoperative identification of cancerous tissue, in near–real-time.
http://stm.sciencemag.org/content/5/194/194ra93.abstract
35 Retinoic Acid and Arsenic Trioxide for Acute Promyelocytic Leukemia.
http://www.nejm.org/doi/full/10.1056/NEJMoa1300874
34 Nivolumab plus Ipilimumab in Advanced Melanoma.
http://www.nejm.org/doi/full/10.1056/NEJMoa1302369?query=featured_home
33 Cyclophosphamide Triggers Follicle Activation and “Burnout”; AS101 Prevents Follicle Loss and Preserves Fertility.
http://stm.sciencemag.org/content/5/185/185ra62.abstract
32 A No-Prophylaxis Platelet-Transfusion Strategy for Hematologic Cancers.
http://www.nejm.org/doi/full/10.1056/NEJMoa1212772
31 Ambient mass spectrometry for the intraoperative molecular diagnosis of human brain tumors.
http://www.pnas.org/content/110/5/1611.abstract
30 Pazopanib and paclitaxel produce cytotoxic synergy in thyroid cancer models through inhibition of aurora kinase A.
http://stm.sciencemag.org/content/5/166/166ra3.abstract
29 In vivo assessment of cancerous tumors using boron doped diamond microelectrode.
http://www.nature.com/srep/2012/121129/srep00901/full/srep00901.html
28 An Inv(16)(p13.3q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein Defines an Aggressive Subtype of Pediatric Acute Megakaryoblastic Leukemia.
http://www.cell.com/cancer-cell/abstract/S1535-6108(12)00438-2
27 Peripheral-Blood Stem Cells versus Bone Marrow from Unrelated Donors.
http://www.nejm.org/doi/full/10.1056/NEJMoa1203517
26 Image analysis of breast cancer tissue improves and complements genomic data to predict patient survival.
http://stm.sciencemag.org/content/4/157/157ra143.abstract
25 Minnelide prevents tumor formation, causes tumor regression, and increases survival in multiple models of pancreatic cancer.
http://stm.sciencemag.org/content/4/156/156ra139.abstract
24 Successful cryopreservation of human ovarian cortex tissues using supercooling.
http://www.nature.com/srep/2012/120727/srep00537/full/srep00537.html
23 Serum DKK1 as a protein biomarker for the diagnosis of hepatocellular carcinoma: a large-scale, multicentre study.
http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(12)70233-4/abstract
22 Google Goes Cancer: Improving Outcome Prediction for Cancer Patients by Network-Based Ranking of Marker Genes.
http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1002511
21 Efficacy and Safety of Vismodegib in Advanced Basal-Cell Carcinoma.
http://www.nejm.org/doi/full/10.1056/NEJMoa1113713
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