118 A brain–spine interface alleviating gait deficits after spinal cord injury in primates.
http://www.nature.com/nature/journal/v539/n7628/full/nature20118.html
117 The BACE1 inhibitor verubecestat safely reduces β-amyloid deposition in rats, monkeys, healthy human subjects, and patients with Alzheimer’s disease.
http://stm.sciencemag.org/content/8/363/363ra150
116 A levodopa powder delivered by a breath-actuated inhaler produced a rapid increase in plasma drug concentrations and improved motor function during OFF episodes in patients with Parkinson’s disease.
http://stm.sciencemag.org/content/8/360/360ra136
115 Randomized Trial of Thymectomy in Myasthenia Gravis.
http://www.nejm.org/doi/full/10.1056/NEJMoa1602489
114 Addition of a non-immersive virtual reality component to treadmill training to reduce fall risk in older adults.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)31325-3/fulltext
113 Dexmedetomidine for prevention of delirium in elderly patients after non-cardiac surgery.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)30580-3/fulltext
112 Adjunctive everolimus therapy for treatment-resistant focal-onset seizures associated with tuberous sclerosis (EXIST-3).
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)31419-2/fulltext
111 Human neural stem cells in patients with chronic ischaemic stroke (PISCES): a phase 1, first-in-man study.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)30513-X/fulltext
110 Long-Term Training with a Brain-Machine Interface-Based Gait Protocol Induces Partial Neurological Recovery in Paraplegic Patients.
http://www.nature.com/articles/srep30383
109 Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)30374-9/abstract
108 Immunoablation and autologous haemopoietic stem-cell transplantation for aggressive multiple sclerosis.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)30169-6/abstract
107 Prenatal Nicotine Exposure and Risk of Schizophrenia Among Offspring in a National Birth Cohort.
http://ajp.psychiatryonline.org/doi/abs/10.1176/appi.ajp.2016.15060800?journalCode=ajp&
106 Signals recorded from motor cortex—through an intracortical implant—can be linked in real-time to activation of forearm muscles to restore movement in a paralysed human.
http://www.nature.com/nature/journal/v533/n7602/full/nature17435.html
105 Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)30272-0/abstract
104 One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke.
http://www.nejm.org/doi/full/10.1056/NEJMoa1412981
103 Hypoxia as a therapy for mitochondrial disease.
http://science.sciencemag.org/content/352/6281/54
102 Genetic variants associated with response to lithium treatment in bipolar disorder.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)00143-4/abstract
101 Long-acting cocaine hydrolase for addiction therapy.
http://www.pnas.org/content/113/2/422.abstract
100 Riluzole blocks perioperative ischemia-reperfusion injury and enhances postdecompression outcomes in cervical spondylotic myelopathy.
http://stm.sciencemag.org/content/7/316/316ra194
99 Genotyping of children with congenital heart disease may identify those at high risk of neurodevelopmental disorders.
http://www.sciencemag.org/content/350/6265/1262.abstract
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