Organic Chemistry

Articles:
74 Here, a method is described by which to generate all possible stereoisomers of certain amino alcohols—a protocol that should see use in drug discovery and development, where it is important to determine the differing effects of stereoisomeric drug candidates.
http://www.nature.com/nature/journal/v532/n7599/full/nature17191.html

73 Nineteen-step total synthesis of (+)-phorbol.
http://www.nature.com/nature/journal/v532/n7597/full/nature17153.html

72 Light-driven oxidation of polysaccharides by photosynthetic pigments and a metalloenzyme.
http://www.nature.com/ncomms/2016/160404/ncomms11134/full/ncomms11134.html

71 Direct synthesis of Z-alkenyl halides through catalytic cross-metathesis.
http://www.nature.com/nature/journal/v531/n7595/full/nature17396.html

70 Molten salts at intermediate temperatures enable efficient carbonate-promoted carboxylation of very weakly acidic C–H bonds, revealing a new way to transform inedible biomass and carbon dioxide into valuable feedstock chemicals.
http://www.nature.com/nature/journal/v531/n7593/full/nature17185.html

69 Asymmetric copper-catalyzed C-N cross-couplings induced by visible light.
http://science.sciencemag.org/content/351/6274/681.abstract

68 Organometallic palladium reagents for cysteine bioconjugation.
http://www.nature.com/nature/journal/v526/n7575/full/nature15739.html

67 Iron-catalysed tritiation of pharmaceuticals.
http://www.nature.com/nature/journal/v529/n7585/full/nature16464.html

66 Network-analysis-guided synthesis of weisaconitine D and liljestrandinine.
http://www.nature.com/nature/journal/v528/n7583/full/nature16440.html

65 Efficient green methanol synthesis from glycerol.
http://www.nature.com/nchem/journal/v7/n12/abs/nchem.2345.html

64 An encapsulating catalyst accelerates carbon-carbon bond formation from transition metal complexes within its cavity.
http://www.sciencemag.org/content/350/6265/1235.abstract

63 Total synthesis of palau’amine.
http://www.nature.com/ncomms/2015/151104/ncomms9731/full/ncomms9731.html

62 Hydrogenation of carboxylic acids with a homogeneous cobalt catalyst.
http://www.sciencemag.org/content/350/6258/298.abstract

61 A concise synthesis of (+)-batzelladine B from simple pyrrole-based starting materials.
http://www.nature.com/nature/journal/v525/n7570/full/nature14902.html

60 Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades.
http://www.sciencemag.org/content/349/6255/1525.abstract

59 Site-selective arene C-H amination via photoredox catalysis.
http://www.sciencemag.org/content/349/6254/1326.abstract

58 Cationic mononuclear ruthenium carboxylates as catalyst prototypes for self-induced hydrogenation of carboxylic acids.
http://www.nature.com/ncomms/2015/150825/ncomms9140/full/ncomms9140.html

57 An inorganic ring-shaped compound manifests electronic stabilization properties analogous to benzene’s.
http://www.sciencemag.org/content/348/6238/1001.abstract

56 A method to form carbon-nitrogen bonds via nitro group reduction could streamline synthetic routes in medicinal chemistry.
http://www.sciencemag.org/content/348/6237/886.abstract

55 Self-assembly of dynamic orthoester cryptates.
http://www.nature.com/ncomms/2015/150522/ncomms8129/full/ncomms8129.html

54 Total synthesis of (+)-gelsemine via an organocatalytic Diels–Alder approach.
http://www.nature.com/ncomms/2015/150521/ncomms8204/full/ncomms8204.html

53 Synthesis of many different types of organic small molecules using one automated process.
http://www.sciencemag.org/content/347/6227/1221

52 Carbon–carbon bond activation of cyclobutenones enabled by the addition of chiral organocatalyst to ketone.
http://www.nature.com/ncomms/2015/150205/ncomms7207/full/ncomms7207.html

51 Metal-catalysed azidation of tertiary C–H bonds suitable for late-stage functionalization.
http://www.nature.com/nature/journal/v517/n7536/full/nature14127.html

50 A catalyst to selectively reverse a common chemical reaction offers versatile opportunities in molecular synthesis.
http://www.sciencemag.org/content/347/6217/56.abstract

49 One-pot room-temperature conversion of cyclohexane to adipic acid by ozone and UV light.
http://www.sciencemag.org/content/346/6216/1495.abstract

48 Crystalline-gradient polycarbonates prepared from enantioselective terpolymerization of meso-epoxides with ​CO2.
http://www.nature.com/ncomms/2014/141205/ncomms6687/full/ncomms6687.html

47 Iron catalysed direct alkylation of amines with alcohols.
http://www.nature.com/ncomms/2014/141126/ncomms6602/full/ncomms6602.html

46 Formic-acid-induced depolymerization of oxidized lignin to aromatics.
http://www.nature.com/nature/journal/v515/n7526/full/nature13867.html

45 A network of sodium and magnesium ions helps direct double deprotonation of aryl rings.
http://www.sciencemag.org/content/346/6211/834.abstract

Free Images for Presentation: sunipix SUNIPIX