69 Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain.
http://www.nature.com/nature/journal/v511/n7511/full/nature13396.html
68 A crystal structure shows how botulinum neurotoxin crosses the host intestinal epithelial barrier, causing toxicity.
http://www.sciencemag.org/content/344/6190/1405.abstract
67 Crystal structure of the human glucose transporter GLUT1.
http://www.nature.com/nature/journal/v510/n7503/full/nature13306.html
66 Crystal structure of a heterotetrameric NMDA receptor ion channel.
http://www.sciencemag.org/content/344/6187/992.abstract
65 The crystal structure of an antifreeze protein shows a polypentagonal network of water in the protein core.
http://www.sciencemag.org/content/343/6172/795.abstract
64 A highly specific chemical crosslinking method is used to trap a complex between an acyl carrier protein and a fatty acid dehydratase during fatty acid biosynthesis; subsequent X-ray crystallography, NMR spectroscopy and molecular dynamics simulations techniques enable the detailed study of this complex.
http://www.nature.com/nature/journal/v505/n7483/full/nature12810.html
63 Structural analysis of human 2′-O-ribose methyltransferases involved in mRNA cap structure formation.
http://www.nature.com/ncomms/2014/140109/ncomms4004/full/ncomms4004.html
62 Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A.
http://www.nature.com/nature/journal/v505/n7481/full/nature12732.html
61 The structure of a human serotonin receptor was solved using a free-electron laser to analyze microcrystals.
https://www.sciencemag.org/content/342/6165/1521.abstract
60 Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer.
https://www.sciencemag.org/content/342/6165/1484.abstract
59 Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer.
https://www.sciencemag.org/content/342/6165/1477.abstract
58 Activation and allosteric modulation of a muscarinic acetylcholine receptor.
http://www.nature.com/nature/journal/v504/n7478/full/nature12735.html
57 Structure of the TRPV1 ion channel determined by electron cryo-microscopy.
http://www.nature.com/nature/journal/v504/n7478/full/nature12822.html
56 Hepatitis C Virus E2 Envelope Glycoprotein Core Structure.
http://www.sciencemag.org/content/342/6162/1090.abstract
55 Rational Design of a Biomimetic Cell Penetrating Peptide Library.
http://pubs.acs.org/doi/abs/10.1021/nn4027382
54 Automatic protein structure solution from weak X-ray data.
http://www.nature.com/ncomms/2013/131115/ncomms3777/full/ncomms3777.html
53 Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs.
http://www.nature.com/nature/journal/v503/n7475/full/nature12595.html
52 The yeast transcription pre-initiation complex has a bi-lobed structure that may reflect the assembly pathway of the complex.
http://www.sciencemag.org/content/342/6159/1238724.abstract
51 The X-ray crystal structure of the Drosophila dopamine transporter bound to the antidepressant drug nortriptyline is presented, providing the first crystal structure of a eukaryotic neurotransmitter sodium symporter.
http://www.nature.com/nature/journal/v503/n7474/full/nature12533.html
50 RNA polymerase I structure and transcription regulation.
http://www.nature.com/nature/journal/v502/n7473/full/nature12712.html
|
