376 The regenerative properties of muscle stem cells decline with age as the stem cells enter an irreversible state of senescence; a study of mouse muscle stem cells reveals that entry into senescence is an autophagy-dependent process and promoting autophagy in old satellite cells can reverse senescence and restore their regenerative properties in an injury model.
http://www.nature.com/nature/journal/v529/n7584/full/nature16187.html
375 Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration.
http://www.nature.com/nature/journal/v528/n7583/full/nature16460.html
374 Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation.
http://www.nature.com/nmat/journal/v14/n12/abs/nmat4407.html
373 Drosophila intestinal stem cells (ISCs) respond to changes in diet, particularly L-glutamate levels, by modulating Ca2+ signalling to adapt their proliferation rate; furthermore, Ca2+ is shown to be central to the response of ISCs to a wide range of dietary and stress stimuli.
http://www.nature.com/nature/journal/v528/n7581/full/nature16170.html
372 By comparing the metabolomes, transcriptomes and epigenomes of human pluripotent stem cell lines, Sperber et al. show that interplay between the metabolome and histone modifications drives the metabolic switch from naive to primed pluripotency.
http://www.nature.com/ncb/journal/v17/n12/abs/ncb3264.html
371 Generation of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue.
http://www.nature.com/ncomms/2015/151117/ncomms9896/full/ncomms9896.html
370 Yap-dependent reprogramming of Lgr5+ stem cells drives intestinal regeneration and cancer.
http://www.nature.com/nature/journal/v526/n7575/full/nature15382.html
369 Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis.
http://www.nature.com/nature/journal/v526/n7574/full/nature15695.html
368 Urine excretion strategy for stem cell-generated embryonic kidneys.
http://www.pnas.org/content/112/42/12980
367 Sleep disruption impairs haematopoietic stem cell transplantation in mice.
http://www.nature.com/ncomms/2015/151014/ncomms9516/full/ncomms9516.html
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