151 Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development.
http://www.jci.org/articles/view/61598
150 MicroRNA-21 contributes to fibrosis in the kidney by posttranscriptionally regulating lipid metabolism genes.
http://stm.sciencemag.org/content/4/121/121ra18.abstract
149 Octopus potassium channels function efficiently at different temperatures due to RNA editing and not genetic differences.
http://www.sciencemag.org/content/335/6070/848.abstract
148 Transcriptome Analysis of the Model Protozoan, Tetrahymena thermophila, Using Deep RNA Sequencing.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0030630
147 Extensive DNA Damage-Induced Sumoylation Contributes to Replication and Repair and Acts in Addition to the Mec1 Checkpoint.
http://www.cell.com/molecular-cell/abstract/S1097-2765(11)00995-6
146 Repeat administration of gene therapy to the contralateral retina of three congenitally blind patients was safe and resulted in improved vision.
http://stm.sciencemag.org/content/4/120/120ra15.abstract
145 The enzyme that maintains DNA methylation in eukaryotes flips out the target C base in hemimethylated DNA for methylation.
http://www.sciencemag.org/content/335/6069/709.abstract
144 Ferric, not ferrous, heme activates RNA-binding protein DGCR8 for primary microRNA processing.
http://www.pnas.org/content/109/6/1919.abstract
143 Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells.
http://www.nature.com/ncb/journal/v14/n2/abs/ncb2422.html
142 New methods for analyzing ligand-receptor binding under physiologic conditions in cell-based assays and living animals are much needed for the testing and validation of candidate therapeutic agents targeting ligand-receptor binding. Here, Kathryn Luker and her colleagues developed a molecular imaging assay for ligand-receptor binding based on Gaussia luciferase complementation, focusing on chemokine CXCL12 and its chemokine receptors CXCR4 and CXCR7, although the assay could be applied more broa
http://www.nature.com/nm/journal/v18/n1/abs/nm.2590.html
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