321 Mutations in a transfer RNA expressed in the nervous system stall ribosomes and can cause cell death if ribosome recycling fails.
http://www.sciencemag.org/content/345/6195/455.abstract
320 Microinjection free delivery of miRNA inhibitor into zygotes.
http://www.nature.com/srep/2014/140624/srep05417/full/srep05417.html
319 Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing.
http://www.nature.com/nbt/journal/v32/n6/abs/nbt.2908.html
318 An enzyme linked to cell death in animal cells protects yeast cells from misfolded protein aggregates.
http://www.sciencemag.org/content/344/6190/1389.abstract
317 Mass-spectrometry-based draft of the human proteome.
http://www.nature.com/nature/journal/v509/n7502/full/nature13319.html
316 A draft map of the human proteome.
http://www.nature.com/nature/journal/v509/n7502/full/nature13302.html
315 The molecular basis for mating-type determination in the ciliate Paramecium has been elucidated, revealing a novel function for a class of small RNAs — these scnRNAs are typically involved in reprogramming the Paramecium genome during sexual reproduction by recognizing and excising transposable elements, but they are now found to be co-opted to switch off expression of the newly identified mating-type gene mtA by excising its promoter, and to mediate epigenetic inheritance of mating types acro
http://www.nature.com/nature/journal/v509/n7501/full/nature13318.html
314 Metagenomic analysis reveals extensive and diverse stop codon reassignments among environmental microbes and phages.
http://www.sciencemag.org/content/344/6186/909.abstract
313 Components of an elusive swelling-activated anion channel are identified and form a structurally new class of channel.
http://www.sciencemag.org/content/344/6184/634.abstract
312 Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis.
http://www.pnas.org/content/111/18/E1823.abstract
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