503 Developmental cell programs are co-opted in inflammatory skin disease.
https://science.sciencemag.org/content/371/6527/eaba6500
502 Loss of tubulin glycylation affects male fertility, owing to sperm motility defects, and perturbs axonemal dynein conformations.
https://science.sciencemag.org/content/371/6525/eabd4914
501 Commensal-driven immune zonation of the liver promotes host defence.
https://www.nature.com/articles/s41586-020-2977-2
500 Single-Molecule Imaging Reveals Translation of mRNAs Localized to Stress Granules.
https://www.cell.com/cell/fulltext/S0092-8674(20)31527-0
499 Multilayer 3D reconstitution of bladder stem cells with stromal cells enables recapitulation of the architecture and molecular functions of bladder tissue.
https://www.nature.com/articles/s41586-020-3034-x
498 Single-cell and single-nucleus RNA sequencing are used to construct a cellular atlas of the human heart that will aid further research into cardiac physiology and disease.
https://www.nature.com/articles/s41586-020-2797-4
497 Gene expression is examined at the single-cell level during early human development.
https://science.sciencemag.org/content/370/6518/eaba7721
496 Down-regulation of Beclin1 promotes direct cardiac reprogramming.
https://stm.sciencemag.org/content/12/566/eaay7856
495 O-glycan–rich mucus secretion segregates colon microbiota from host cells to prevent inflammation during fecal elimination.
https://science.sciencemag.org/content/370/6515/467
494 An organoid-based screening platform maps the genetic interactions underlying intestinal development and regeneration, showing that retinoic acid metabolism maintains the balance between regeneration and homeostasis, and that an antagonist of the retinoid X receptor promotes regeneration in vivo.
https://www.nature.com/articles/s41586-020-2776-9
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