494 BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells.
http://www.nature.com/ncomms/2015/150109/ncomms6987/full/ncomms6987.html
493 Only three driver gene mutations are required for the development of lung and colorectal cancers.
http://www.pnas.org/content/112/1/118.abstract
492 Mice deficient in Rbm38, a target of the p53 family, are susceptible to accelerated aging and spontaneous tumors.
http://www.pnas.org/content/111/52/18637.abstract
491 In vivo anticancer activity of rhomboidal Pt(II) metallacycles.
http://www.pnas.org/content/111/52/18448.abstract
490 Using transplantation and lineage-tracing strategies, protein C receptor is identified as a marker of mammary stem cells in mice, with potential implications for understanding the initiation of breast cancer.
http://www.nature.com/nature/journal/v517/n7532/full/nature13851.html
489 Variation in cancer risk among tissues can be explained by the number of stem cell divisions.
http://www.sciencemag.org/content/347/6217/78.abstract
488 Postsurgical Adjuvant Tumor Therapy by Combining Anti-Angiopoietin-2 and Metronomic Chemotherapy Limits Metastatic Growth.
http://www.cell.com/cancer-cell/abstract/S1535-6108(14)00456-5
487 A BCL6/BCOR/SIRT1 Complex Triggers Neurogenesis and Suppresses Medulloblastoma by Repressing Sonic Hedgehog Signaling.
http://www.cell.com/cancer-cell/abstract/S1535-6108(14)00451-6
486 Acetate Dependence of Tumors.
http://www.cell.com/cell/abstract/S0092-8674(14)01451-2
485 Acetate Is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases.
http://www.cell.com/cell/abstract/S0092-8674(14)01502-5
484 In vivo selective cancer-tracking gadolinium eradicator as new-generation photodynamic therapy agent.
http://www.pnas.org/content/111/51/E5492.abstract
483 A stem cell model of a lethal brain tumor in children shows how a recurrent histone mutation leads to cancer.
http://www.sciencemag.org/content/346/6216/1529.abstract
482 Dissecting the clonal origins of childhood acute lymphoblastic leukemia by single-cell genomics.
http://www.pnas.org/content/111/50/17947.abstract
481 The Wilms’ tumour suppressor Wt1 is a major regulator of tumour angiogenesis and progression.
http://www.nature.com/ncomms/2014/141216/ncomms6852/full/ncomms6852.html
480 Detection of cancer biomarkers in serum using a hybrid mechanical and optoplasmonic nanosensor.
http://www.nature.com/nnano/journal/v9/n12/abs/nnano.2014.250.html
479 Leukemia-associated mutations drive cell growth by creating a powerful transcriptional enhancer upstream of an oncogene.
http://www.sciencemag.org/content/346/6215/1373.abstract
478 Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma.
http://www.nature.com/nm/journal/v20/n12/abs/nm.3716.html
477 Disruption of FAT10–MAD2 binding inhibits tumor progression.
http://www.pnas.org/content/111/49/E5282.abstract
476 RHOA inactivation enhances Wnt signalling and promotes colorectal cancer.
http://www.nature.com/ncomms/2014/141121/ncomms6458/full/ncomms6458.html
475 Discovery and characterization of small molecules that target the GTPase Ral.
http://www.nature.com/nature/journal/v515/n7527/full/nature13713.html
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