614 Neutrophils support lung colonization of metastasis-initiating breast cancer cells.
http://www.nature.com/nature/journal/v528/n7582/full/nature16140.html
613 The transcription factor ATF2 promotes melanoma metastasis by suppressing protein fucosylation.
http://stke.sciencemag.org/content/8/406/ra124.abstract
612 Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
http://www.sciencemag.org/content/350/6266/1391.abstract
611 TLR9 ligation in pancreatic stellate cells promotes tumorigenesis.
http://jem.rupress.org/content/212/12/2077.abstract
610 Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation.
http://www.nature.com/nchem/journal/v7/n12/abs/nchem.2381.html
609 Synthetic lethal targeting of oncogenic transcription factors in acute leukemia by PARP inhibitors.
http://www.nature.com/nm/journal/v21/n12/abs/nm.3993.html
608 Brain tumour cells interconnect to a functional and resistant network.
http://www.nature.com/nature/journal/v528/n7580/full/nature16071.html
607 An endoscope with integrated transparent bioelectronics and theranostic nanoparticles for colon cancer treatment.
http://www.nature.com/ncomms/2015/151130/ncomms10059/full/ncomms10059.html
606 An epithelial-to-mesenchymal transition (EMT) lineage-tracing system in a mouse model of breast-to-lung metastasis reveals that although some cells undergo EMT in a primary epithelial tumour, the lung metastases mainly arise from cells that have not undergone EMT; in addition, cells that have undergone EMT appear more resistant to chemotherapy.
http://www.nature.com/nature/journal/v527/n7579/full/nature15748.html
605 Trastuzumab emtansine (T-DM1) renders HER2+ breast cancer highly susceptible to CTLA-4/PD-1 blockade.
http://stm.sciencemag.org/content/7/315/315ra188
604 Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy.
http://www.sciencemag.org/content/350/6264/1084.abstract
603 Gut microbes modulate the effectiveness of cancer immunotherapies in mice.
http://www.sciencemag.org/content/350/6264/1079.abstract
602 An immune cell subset called patrolling monocytes prevents tumor lung metastasis in mice.
http://www.sciencemag.org/content/350/6263/985.abstract
601 Formyl peptide receptor 1 helps the immune system sense dying tumor cells.
http://www.sciencemag.org/content/350/6263/972.abstract
600 Targeting LGR5+ cells with an antibody-drug conjugate for the treatment of colon cancer.
http://stm.sciencemag.org/content/7/314/314ra186
599 ASS1, a urea cycle enzyme, promotes cancer cell proliferation by facilitating pyrimidine synthesis via CAD (carbamoyl-phosphate synthase 2, aspartate transcarbamylase, and dihydroorotase complex) activation.
http://www.nature.com/nature/journal/v527/n7578/full/nature15529.html
598 MicroRNA–mRNA interactions underlying colorectal cancer molecular subtypes.
http://www.nature.com/ncomms/2015/151117/ncomms9878/full/ncomms9878.html
597 Antibody-Modified Reduced Graphene Oxide Films with Extreme Sensitivity to Circulating Tumor Cells.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201502615/full
596 Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma.
http://www.nature.com/ncomms/2015/151110/ncomms9839/full/ncomms9839.html
595 Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy.
http://www.nature.com/nature/journal/v527/n7577/full/nature15520.html
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