874 Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell–driven tumor immunity.
http://science.sciencemag.org/content/359/6383/1537
873 The protein histidine phosphatase LHPP is a tumour suppressor.
https://www.nature.com/articles/nature26140
872 Peptides of pHLIP family for targeted intracellular and extracellular delivery of cargo molecules to tumors.
http://www.pnas.org/content/115/12/E2811
871 DNA methylation-based classification of central nervous system tumours.
https://www.nature.com/articles/nature26000
870 Extended release of perioperative immunotherapy prevents tumor recurrence and eliminates metastases.
http://stm.sciencemag.org/content/10/433/eaar1916
869 In mice, tumor cells can metastasize via lymph node blood vessels.
http://science.sciencemag.org/content/359/6382/1408
868 Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice.
http://science.sciencemag.org/content/359/6382/1403
867 A novel chimeric antigen receptor containing a JAK–STAT signaling domain mediates superior antitumor effects.
https://www.nature.com/articles/nm.4478
866 A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo.
https://www.nature.com/articles/nbt.4071
865 Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours.
https://www.nature.com/articles/nature25795
864 The Cdx2 homeobox gene suppresses intestinal tumorigenesis through non–cell-autonomous mechanisms.
http://jem.rupress.org/content/215/3/911
863 Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity.
http://jem.rupress.org/content/215/3/877
862 A commensal strain of Staphylococcus epidermidis protects against skin neoplasia.
http://advances.sciencemag.org/content/4/2/eaao4502
861 Patient-derived organoids model treatment response of metastatic gastrointestinal cancers.
http://science.sciencemag.org/content/359/6378/920
860 Naked mole rats can undergo developmental, oncogene-induced and DNA damage-induced cellular senescence.
http://www.pnas.org/content/115/8/1801
859 Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy.
http://stm.sciencemag.org/content/10/428/eaaf7444
858 Renal cell cancers with mutations in a specific chromatin regulator have a better clinical response to immunotherapy.
http://science.sciencemag.org/content/359/6377/801
857 Inactivation of a chromatin remodeling complex in tumor cells enhances their sensitivity to killing by T cells.
http://science.sciencemag.org/content/359/6377/770
856 Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury.
https://www.nature.com/articles/nm.4470
855 Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models.
https://www.nature.com/articles/nm.4464
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