Cancer Biology

893 PRDM1 silences stem cell-related genes and inhibits proliferation of human colon tumor organoids.

892 Cross-talk between bacteria and bile acid promotes natural killer T cell antitumor immunity in the liver.

891 A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent.

890 Circular ssDNA can sequester inhibitory microRNAs to restore tumor suppressor gene function, thereby inhibiting tumor progression.

889 KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.

888 Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells.

887 Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis

886 An online resource maps the molecular genetic features of glioblastoma, a lethal brain cancer, to its anatomic features.

885 Development of a stress response therapy targeting aggressive prostate cancer.

884 p52 expression enhances lung cancer progression.

883 Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer.

882 Dual inhibition of MDMX and MDM2 by an α-helical p53-stapled peptide (ALRN-6924) results in robust antitumor activity in acute myeloid leukemia.

881 CK1α suppresses lung tumour growth by stabilizing PTEN and inducing autophagy.

880 Chimeric antigen receptor (CAR)-T cells expressing the cytokines IL-7 and CCL19 show improved clearance of established solid tumors in mice.

879 In chronic myelogenous leukemia, leukemia stem cell function requires a microRNA that is provided by bone marrow endothelial cells.

878 The small molecule H3B-8800 selectively modulates RNA splicing to preferentially kill tumor cells bearing mutations in genes encoding spliceosome components.

877 Targeting tyrosine kinase receptors that share the feedback inhibitor PTPN12 leads to broad spectrum therapeutic suppression of triple-negative breast cancer.

876 Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer.

875 Reassembly of 89Zr‐Labeled Cancer Cell Membranes into Multicompartment Membrane‐Derived Liposomes for PET‐Trackable Tumor‐Targeted Theranostics.

874 Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell–driven tumor immunity.

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