483 Complete biosynthesis of the bisbenzylisoquinoline alkaloids guattegaumerine and berbamunine in yeast.
https://www.pnas.org/content/118/51/e2112520118
482 A nanopore-based approach was developed for reading individual peptides with sensitivity to single-amino-acid substitutions.
https://www.science.org/doi/10.1126/science.abl4381
481 CRISPR-Cas9 effectors facilitate generation of single-sex litters and sex-specific phenotypes.
https://www.nature.com/articles/s41467-021-27227-2
480 Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species.
https://www.cell.com/cell/fulltext/S0092-8674(21)01002-3
479 Engineering genetic devices for in vivo control of therapeutic T cell activity triggered by the dietary molecule resveratrol.
https://www.pnas.org/content/118/34/e2106612118
478 Minute-scale detection of SARS-CoV-2 using a low-cost biosensor composed of pencil graphite electrodes.
https://www.pnas.org/content/118/30/e2106724118
477 Reversed-engineered human alveolar lung-on-a-chip model
https://www.pnas.org/content/118/19/e2016146118
476 Polypeptide organic radical batteries.
https://www.nature.com/articles/s41586-021-03399-1
475 A soft, wearable microfluidic platform collects and quantitatively analyzes sweat biomarkers to improve the diagnosis of cystic fibrosis.
https://stm.sciencemag.org/content/13/587/eabd8109
474 An enzyme-based biosensor for monitoring and engineering protein stability in vivo.
https://www.pnas.org/content/118/13/e2101618118
|
