705 Targeting renal cell carcinoma with a HIF-2 antagonist.
http://www.nature.com/nature/journal/v539/n7627/full/nature19796.html
704 Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy.
http://www.nature.com/articles/ncomms13354
703 Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1.
http://www.nature.com/articles/ncomms6212
702 Inflammation-Triggered Cancer Immunotherapy by Programmed Delivery of CpG and Anti-PD1 Antibody.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201506312/full
701 The epichaperome is an integrated chaperome network that facilitates tumour survival.
http://www.nature.com/nature/journal/v538/n7625/full/nature19807.html
700 A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns.
http://www.nature.com/nature/journal/v538/n7625/full/nature19823.html
699 An AMP-activated protein kinase–stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice.
http://www.nature.com/nm/journal/v22/n10/abs/nm.4171.html
698 Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models.
http://www.nature.com/nm/journal/v22/n10/abs/nm.4181.html
697 Local triple-combination therapy results in tumour regression and prevents recurrence in a colon cancer model.
http://www.nature.com/nmat/journal/v15/n10/abs/nmat4707.html
696 L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity.
http://www.cell.com/cell/fulltext/S0092-8674(16)31313-7
695 Anti-VEGF therapy enhances mechanical barriers to therapy in colorectal cancer liver metastases by increasing hyaluronan deposition.
http://stm.sciencemag.org/content/8/360/360ra135
694 Mechanism of inhibition of the tumor suppressor Patched by Sonic Hedgehog.
http://www.pnas.org/content/113/40/E5866.abstract
693 Integrative analyses reveal a long noncoding RNA-mediated sponge regulatory network in prostate cancer.
http://www.nature.com/articles/ncomms10982
692 70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer.
http://www.nejm.org/doi/full/10.1056/NEJMoa1602253
691 Ionic immune suppression within the tumour microenvironment limits T cell effector function.
http://www.nature.com/nature/journal/v537/n7621/full/nature19364.html
690 A PGC1α-mediated transcriptional axis suppresses melanoma metastasis.
http://www.nature.com/nature/journal/v537/n7620/full/nature19347.html
689 Precision glycocalyx editing as a strategy for cancer immunotherapy.
http://www.pnas.org/content/113/37/10304
688 Combined targeting of BCL-2 and BCR-ABL tyrosine kinase eradicates chronic myeloid leukemia stem cells.
http://stm.sciencemag.org/content/8/355/355ra117.abstract
687 A CD19 chimeric antigen receptor–modified T cell product with defined composition has potent antitumor activity.
http://stm.sciencemag.org/content/8/355/355ra116.abstract
686 G9a/RelB regulates self-renewal and function of colon-cancer-initiating cells by silencing Let-7b and activating the K-RAS/β-catenin pathway.
http://www.nature.com/ncb/journal/v18/n9/abs/ncb3395.html
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