Biochemistry

Articles:

289  Tungsten enzymes play a role in detoxifying food and antimicrobial aldehydes in the human gut microbiome.
https://www.pnas.org/content/118/43/e2109008118

288  Cell-free chemoenzymatic starch synthesis from carbon dioxide.
https://www.science.org/doi/10.1126/science.abh4049

287  Prospecting for natural products by genome mining and microcrystal electron diffraction.
https://www.nature.com/articles/s41589-021-00834-2

286  In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels.
https://www.nature.com/articles/s41587-021-00933-4

285  A microfluidic platform for high-throughput quantitative biochemistry reveals enzyme architectures that shape function.
https://science.sciencemag.org/content/373/6553/eabf8761

284  In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates.
https://www.nature.com/articles/s41586-021-03534-y

283  Discovery, characterization and engineering of ligases for amide synthesis.
https://www.nature.com/articles/s41586-021-03447-w

282  High CO2 levels drive the TCA cycle backwards towards autotrophy.
https://www.nature.com/articles/s41586-021-03456-9

281  Melanocortin 3 receptor-expressing neurons in the ventromedial hypothalamus promote glucose disposal.
https://www.pnas.org/content/118/15/e2103090118

280  X-ray crystal structures reveal how anticoagulants inhibit a vitamin K regenerating enzyme.
https://science.sciencemag.org/content/371/6524/eabc5667

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