289  Tungsten enzymes play a role in detoxifying food and antimicrobial aldehydes in the human gut microbiome.

288  Cell-free chemoenzymatic starch synthesis from carbon dioxide.

287  Prospecting for natural products by genome mining and microcrystal electron diffraction.

286  In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels.

285  A microfluidic platform for high-throughput quantitative biochemistry reveals enzyme architectures that shape function.

284  In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates.

283  Discovery, characterization and engineering of ligases for amide synthesis.

282  High CO2 levels drive the TCA cycle backwards towards autotrophy.

281  Melanocortin 3 receptor-expressing neurons in the ventromedial hypothalamus promote glucose disposal.

280  X-ray crystal structures reveal how anticoagulants inhibit a vitamin K regenerating enzyme.

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