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Molecular Biology

Molecular Biology

Articles:

699  Toward the simultaneous detection of multiple diseases with a highly cost-effective cell-free DNA methylome test
https://www.pnas.org/doi/10.1073/pnas.2518347123

698  How do RNA molecules distinguish self from non-self?
https://www.pnas.org/doi/10.1073/pnas.2603593123

697  A prophage-encoded abortive infection protein preserves host and prophage spread
https://www.nature.com/articles/s41586-025-10070-6

696  DNA methylation in invertebrate genomes and cell lineage plasticity
https://www.pnas.org/doi/10.1073/pnas.2510416123

695  In vivo base editing of Chd3 rescues behavioural abnormalities in mice
https://www.nature.com/articles/s41586-026-10113-6

694  Programmable genome editing in human cells using RNA-guided bridge recombinases
https://www.science.org/doi/10.1126/science.adz1884

693  N1-Methylpseudouridine directly modulates translation dynamics
https://www.nature.com/articles/s41586-025-09945-5

692  PAF15–PCNA exhaustion governs the strand-specific control of DNA replication
https://www.nature.com/articles/s41586-025-10011-3

691  Methionine-specific nonreversible bioconjugation: Advancing precision protein modification
https://www.pnas.org/doi/10.1073/pnas.2519038123

690  SPARK-seq: A high-throughput platform for aptamer discovery and kinetic profiling
https://www.science.org/doi/10.1126/science.adv6127

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