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Physiology

Physiology

Articles:

157 ER remodelling is a feature of ageing and depends on ER-phagy
https://www.nature.com/articles/s41556-025-01860-1

156 Mitochondrial remodeling in skeletal muscle underlies exercise-induced reversal of age-associated functional decline in mice and humans
https://www.pnas.org/doi/10.1073/pnas.2508286123

155 Lifelong behavioral screen reveals an architecture of vertebrate aging
https://www.science.org/doi/10.1126/science.aea9795

154 Recognition of distinct sleep states in Drosophila uncovers previously obscured homeostatic and circadian control of sleep
https://www.cell.com/current-biology/fulltext/S0960-9822(26)00015-1

153 Host–microbiome mutualism drives urea carbon salvage and acetogenesis during hibernation
https://www.pnas.org/doi/10.1073/pnas.2518978123

152 DNA damage modulates sleep drive in basal cnidarians with divergent chronotypes
https://www.nature.com/articles/s41467-025-67400-5

151 Precancer exercise capacity and metabolism during tumor development coordinate the skeletal muscle–tumor metabolic competition
https://www.pnas.org/doi/10.1073/pnas.2508707122

150 Exercise suppresses DEAF1 to normalize mTORC1 activity and reverse muscle aging
https://www.pnas.org/doi/10.1073/pnas.2508893122

149 A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging.
https://www.science.org/doi/10.1126/science.adp5056

148 Life without sex: Large-scale study links sexlessness to physical, cognitive, and personality traits, socioecological factors, and DNA
https://www.pnas.org/doi/10.1073/pnas.2418257122

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