725 Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation.
http://www.nature.com/nm/journal/v23/n1/abs/nm.4252.html
724 A genome-wide CRISPR screen reveals that FZD5, but none of the other nine Frizzled receptors encoded in the human genome, is a therapeutic vulnerability of pancreatic and colorectal tumors bearing RNF43 mutations.
http://www.nature.com/nm/journal/v23/n1/abs/nm.4219.html
723 Syrosingopine sensitizes cancer cells to killing by metformin.
http://advances.sciencemag.org/content/2/12/e1601756
722 Tumor location determines tissue-specific recruitment of tumor-associated macrophages and antibody-dependent immunotherapy response.
http://immunology.sciencemag.org/content/2/7/eaah6413
721 Prostate cancer cells escape androgen deprivation therapy by morphing into a cell type that does not require androgens.
http://science.sciencemag.org/content/355/6320/78
720 SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer.
http://science.sciencemag.org/content/355/6320/84
719 Molecular profiling of single circulating tumor cells from lung cancer patients.
http://www.pnas.org/content/113/52/E8379.abstract
718 Targeting metastasis-initiating cells through the fatty acid receptor CD36.
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature20791.html
717 Mechanism of early dissemination and metastasis in Her2+ mammary cancer.
http://www.nature.com/nature/journal/v540/n7634/full/nature20609.html
716 NLRC3 is an inhibitory sensor of PI3K–mTOR pathways in cancer.
http://www.nature.com/nature/journal/v540/n7634/full/nature20597.html
715 Early dissemination seeds metastasis in breast cancer.
http://www.nature.com/nature/journal/v540/n7634/full/nature20785.html
714 Bifunctional Platinated Nanoparticles for Photoinduced Tumor Ablation.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201602738/full
713 Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses.
http://www.nature.com/nm/journal/v22/n12/abs/nm.4200.html
712 Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells.
http://www.cell.com/immunity/fulltext/S1074-7613(16)30432-0
711 Regulatory T Cells Exhibit Distinct Features in Human Breast Cancer.
http://www.cell.com/immunity/fulltext/S1074-7613(16)30443-5
710 In vivo, label-free evaluation of mitochondrial function in human skin epithelia noninvasively differentiates healthy from cancerous tissues.
http://stm.sciencemag.org/content/8/367/367ra169
709 Improved cancer immunotherapy by a CD25-mimobody conferring selectivity to human interleukin-2.
http://stm.sciencemag.org/content/8/367/367ra166
708 Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity.
http://www.cell.com/cell-metabolism/fulltext/S1550-4131(16)30541-1
707 LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.
http://www.cell.com/cell-metabolism/fulltext/S1550-4131(16)30427-2
706 Local and transient gene expression primes the liver to resist cancer metastasis.
http://stm.sciencemag.org/content/8/364/364ra153
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