685 Melanoma miRNA trafficking controls tumour primary niche formation.
http://www.nature.com/ncb/journal/v18/n9/abs/ncb3399.html
684 A single dividing cell population with imbalanced fate drives oesophageal tumour growth.
http://www.nature.com/ncb/journal/v18/n9/abs/ncb3400.html
683 TNIK inhibition abrogates colorectal cancer stemness.
http://www.nature.com/articles/ncomms12586
682 Pancreatic adenocarcinoma cells drive autophagy in tumour microenvironment-associated stellate cells, which release alanine that is used by the cancer cells as a carbon source for a variety of metabolic processes in an otherwise nutrient-poor environment.
http://www.nature.com/nature/journal/v536/n7617/full/nature19084.html
681 miR-579-3p controls melanoma progression and resistance to target therapy.
http://www.pnas.org/content/113/34/E5005.abstract
680 A recellularized human colon model identifies cancer driver genes.
http://www.nature.com/nbt/journal/v34/n8/abs/nbt.3586.html
679 Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis.
http://www.nature.com/articles/ncomms12365
678 Human and murine tumour cells induce programmed necrosis (necroptosis) of endothelial cells, which promotes tumour cell extravasation and metastasis.
http://www.nature.com/nature/journal/v536/n7615/full/nature19076.html
677 Tumor-derived circulating endothelial cell clusters in colorectal cancer.
http://stm.sciencemag.org/content/8/345/345ra89
676 Clinical trial of blood-brain barrier disruption by pulsed ultrasound.
http://stm.sciencemag.org/content/8/343/343re2
675 Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy.
http://www.nature.com/nature/journal/v534/n7607/full/nature18300.html
674 Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells.
http://www.nature.com/nature/journal/v534/n7607/full/nature18288.html
673 The metabolic co-regulator PGC1α suppresses prostate cancer metastasis.
http://www.nature.com/ncb/journal/v18/n6/abs/ncb3357.html
672 T cells from healthy human donors may be an important resource for outsourcing cancer immunotherapy.
http://science.sciencemag.org/content/352/6291/1337.abstract
671 SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b.
http://www.cell.com/cell/fulltext/S0092-8674(16)30476-7
670 Blockage of neddylation modification stimulates tumor sphere formation in vitro and stem cell differentiation and wound healing in vivo.
http://www.pnas.org/content/113/21/E2935.abstract
669 Design of a small molecule against an oncogenic noncoding RNA.
http://www.pnas.org/content/113/21/5898.abstract
668 Dormant breast cancer micrometastases reside in specific bone marrow niches that regulate their transit to and from bone.
http://stm.sciencemag.org/content/8/340/340ra73.abstract
667 The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia.
http://stm.sciencemag.org/content/8/339/339ra69.abstract
666 Activation of concurrent apoptosis and necroptosis by SMAC mimetics for the treatment of refractory and relapsed ALL.
http://stm.sciencemag.org/content/8/339/339ra70.abstract
|